| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_152 | dprA | CH53_152 | CH53_1453 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | dprA: DNA protecting protein DprA. | 0.870 |
| CH53_152 | mfd | CH53_152 | CH53_4415 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.424 |
| CH53_152 | recJ | CH53_152 | CH53_2637 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | recJ: single-stranded-DNA-specific exonuclease RecJ. | 0.580 |
| CH53_152 | recQ | CH53_152 | CH53_2009 | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | recQ: ATP-dependent DNA helicase RecQ. | 0.509 |
| dnaG | recJ | CH53_2325 | CH53_2637 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | recJ: single-stranded-DNA-specific exonuclease RecJ. | 0.576 |
| dnaG | uvrD | CH53_2325 | CH53_2000 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | uvrD: DNA helicase II. | 0.508 |
| dprA | CH53_152 | CH53_1453 | CH53_152 | dprA: DNA protecting protein DprA. | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | 0.870 |
| dprA | mfd | CH53_1453 | CH53_4415 | dprA: DNA protecting protein DprA. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.473 |
| dprA | recJ | CH53_1453 | CH53_2637 | dprA: DNA protecting protein DprA. | recJ: single-stranded-DNA-specific exonuclease RecJ. | 0.627 |
| dsbC | recJ | CH53_2636 | CH53_2637 | DSBA-like thioredoxin domain protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | recJ: single-stranded-DNA-specific exonuclease RecJ. | 0.804 |
| dsbC | xerD | CH53_2636 | CH53_2634 | DSBA-like thioredoxin domain protein; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...] | 0.722 |
| mfd | CH53_152 | CH53_4415 | CH53_152 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | comEC_Rec2: DNA internalization-related competence protein ComEC/Rec2. | 0.424 |
| mfd | dprA | CH53_4415 | CH53_1453 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | dprA: DNA protecting protein DprA. | 0.473 |
| mfd | murE | CH53_4415 | CH53_1023 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | UDP-N-acetylmuramyl-tripeptide synthetase family protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.402 |
| mfd | recJ | CH53_4415 | CH53_2637 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | recJ: single-stranded-DNA-specific exonuclease RecJ. | 0.652 |
| mfd | uvrD | CH53_4415 | CH53_2000 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | uvrD: DNA helicase II. | 0.521 |
| mfd | xerD | CH53_4415 | CH53_2634 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Tyrosine recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. Binds cooperatively to specific DNA consensus sequences that are separated from XerC binding sites by a short central region, forming the heterotetrameric XerC-XerD complex that recombines DNA substrates. The complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. In the complex XerD specifically exchanges t [...] | 0.457 |
| mfd | xseA | CH53_4415 | CH53_622 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.590 |
| murE | mfd | CH53_1023 | CH53_4415 | UDP-N-acetylmuramyl-tripeptide synthetase family protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.402 |
| murE | recJ | CH53_1023 | CH53_2637 | UDP-N-acetylmuramyl-tripeptide synthetase family protein; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | recJ: single-stranded-DNA-specific exonuclease RecJ. | 0.603 |