| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bioB | birA | CH53_3184 | CH53_2081 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.952 |
| bioB | dorA | CH53_3184 | CH53_2677 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.900 |
| birA | bioB | CH53_2081 | CH53_3184 | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.952 |
| birA | dorA | CH53_2081 | CH53_2677 | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.900 |
| dmsB | dmsB-2 | CH53_492 | CH53_838 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | 0.902 |
| dmsB | dorA | CH53_492 | CH53_2677 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.645 |
| dmsB | hybB | CH53_492 | CH53_2407 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | Putative membrane protein. | 0.800 |
| dmsB | nifJ | CH53_492 | CH53_4046 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.586 |
| dmsB-2 | dmsB | CH53_838 | CH53_492 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | 0.902 |
| dmsB-2 | dorA | CH53_838 | CH53_2677 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | 0.652 |
| dmsB-2 | hybB | CH53_838 | CH53_2407 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | Putative membrane protein. | 0.800 |
| dmsB-2 | nifJ | CH53_838 | CH53_4046 | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.586 |
| dorA | bioB | CH53_2677 | CH53_3184 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.900 |
| dorA | birA | CH53_2677 | CH53_2081 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.900 |
| dorA | dmsB | CH53_2677 | CH53_492 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | 0.645 |
| dorA | dmsB-2 | CH53_2677 | CH53_838 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | DMSO_dmsB: dimethylsulfoxide reductase, chain B. | 0.652 |
| dorA | gltB | CH53_2677 | CH53_2269 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Glutamine amidotransferases class-II family protein. | 0.646 |
| dorA | hybB | CH53_2677 | CH53_2407 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Putative membrane protein. | 0.740 |
| dorA | napB | CH53_2677 | CH53_556 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | Nitrate reductase cytochrome c-type subunit family protein; Electron transfer subunit of the periplasmic nitrate reductase complex NapAB; Belongs to the NapB family. | 0.665 |
| dorA | napC | CH53_2677 | CH53_555 | Molybdopterin oxidoreductase family protein; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. | napC_nirT: periplasmic nitrate (or nitrite) reductase c-type cytochrome, NapC/NirT family protein. | 0.656 |