| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_11 | mreD | CH53_11 | CH53_2202 | Hypothetical protein. | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | 0.452 |
| CH53_11 | nfuA | CH53_11 | CH53_1567 | Hypothetical protein. | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.567 |
| CH53_11 | rlmM | CH53_11 | CH53_2708 | Hypothetical protein. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.469 |
| CH53_11 | yihI | CH53_11 | CH53_1805 | Hypothetical protein. | Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.402 |
| CH53_1516 | CH53_4118 | CH53_1516 | CH53_4118 | Hypothetical protein; Belongs to the UPF0270 family. | Hypothetical protein; FAD linked oxidase, C-terminal domain protein. | 0.442 |
| CH53_1516 | rlmM | CH53_1516 | CH53_2708 | Hypothetical protein; Belongs to the UPF0270 family. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.418 |
| CH53_1516 | yihI | CH53_1516 | CH53_1805 | Hypothetical protein; Belongs to the UPF0270 family. | Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.448 |
| CH53_4118 | CH53_1516 | CH53_4118 | CH53_1516 | Hypothetical protein; FAD linked oxidase, C-terminal domain protein. | Hypothetical protein; Belongs to the UPF0270 family. | 0.442 |
| CH53_4118 | rlmM | CH53_4118 | CH53_2708 | Hypothetical protein; FAD linked oxidase, C-terminal domain protein. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.430 |
| gcvA | rlmM | CH53_2706 | CH53_2708 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.499 |
| gcvA | ygdD | CH53_2706 | CH53_2707 | Glycine cleavage system transcriptional activator; Belongs to the LysR transcriptional regulatory family. | Hypothetical protein. | 0.573 |
| lpoA | rlmM | CH53_2277 | CH53_2708 | lppC lipofamily protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.402 |
| lpoA | yihI | CH53_2277 | CH53_1805 | lppC lipofamily protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family. | Der GTPase activator family protein; A GTPase-activating protein (GAP) that modifies Der/EngA GTPase function. May play a role in ribosome biogenesis. Belongs to the YihI family. | 0.431 |
| mreD | CH53_11 | CH53_2202 | CH53_11 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | Hypothetical protein. | 0.452 |
| mreD | rlmM | CH53_2202 | CH53_2708 | Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.474 |
| nfuA | CH53_11 | CH53_1567 | CH53_11 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | Hypothetical protein. | 0.567 |
| nfuA | rlmM | CH53_1567 | CH53_2708 | fe/S biogenesis protein nfuA; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | 0.489 |
| rlmM | CH53_11 | CH53_2708 | CH53_11 | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Hypothetical protein. | 0.469 |
| rlmM | CH53_1516 | CH53_2708 | CH53_1516 | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Hypothetical protein; Belongs to the UPF0270 family. | 0.418 |
| rlmM | CH53_4118 | CH53_2708 | CH53_4118 | ftsJ-like methyltransferase family protein; Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily. | Hypothetical protein; FAD linked oxidase, C-terminal domain protein. | 0.430 |