| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| cdsA | dxr | CH53_2726 | CH53_2724 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | 0.851 |
| cdsA | hlpA | CH53_2726 | CH53_2729 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Outer membrane family protein; Belongs to the skp family. | 0.453 |
| cdsA | lpxD | CH53_2726 | CH53_2730 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.556 |
| cdsA | rseP | CH53_2726 | CH53_2727 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | RIP metalloprotease RseP. | 0.880 |
| cdsA | uppS | CH53_2726 | CH53_2725 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.983 |
| cdsA | yaeT | CH53_2726 | CH53_2728 | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | Outer membrane assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | 0.685 |
| degS | gltB | CH53_2259 | CH53_2269 | protease_degS: periplasmic serine peptidase DegS. | Glutamine amidotransferases class-II family protein. | 0.470 |
| degS | rseP | CH53_2259 | CH53_2727 | protease_degS: periplasmic serine peptidase DegS. | RIP metalloprotease RseP. | 0.701 |
| dxr | cdsA | CH53_2724 | CH53_2726 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.851 |
| dxr | lpxD | CH53_2724 | CH53_2730 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.407 |
| dxr | rseP | CH53_2724 | CH53_2727 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | RIP metalloprotease RseP. | 0.710 |
| dxr | uppS | CH53_2724 | CH53_2725 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.950 |
| dxr | yaeT | CH53_2724 | CH53_2728 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP). | Outer membrane assembly complex, YaeT protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. Constitutes, with BamD, the core component of the assembly machinery. | 0.539 |
| gltB | degS | CH53_2269 | CH53_2259 | Glutamine amidotransferases class-II family protein. | protease_degS: periplasmic serine peptidase DegS. | 0.470 |
| gltB | lepB | CH53_2269 | CH53_681 | Glutamine amidotransferases class-II family protein. | sigpep_I_bact: signal peptidase I; Belongs to the peptidase S26 family. | 0.538 |
| gltB | rseP | CH53_2269 | CH53_2727 | Glutamine amidotransferases class-II family protein. | RIP metalloprotease RseP. | 0.615 |
| hlpA | cdsA | CH53_2729 | CH53_2726 | Outer membrane family protein; Belongs to the skp family. | Phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.453 |
| hlpA | lpxD | CH53_2729 | CH53_2730 | Outer membrane family protein; Belongs to the skp family. | UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase LpxD; Catalyzes the N-acylation of UDP-3-O- (hydroxytetradecanoyl)glucosamine using 3-hydroxytetradecanoyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell; Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.956 |
| hlpA | rseP | CH53_2729 | CH53_2727 | Outer membrane family protein; Belongs to the skp family. | RIP metalloprotease RseP. | 0.708 |
| hlpA | uppS | CH53_2729 | CH53_2725 | Outer membrane family protein; Belongs to the skp family. | Di-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. | 0.449 |