| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_2758 | pssA | CH53_2758 | CH53_2759 | Hypothetical protein. | CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.666 |
| CH53_2758 | yfiQ | CH53_2758 | CH53_2760 | Hypothetical protein. | Acetyltransferase family protein. | 0.430 |
| CH53_2761 | yfiQ | CH53_2761 | CH53_2760 | DTW domain protein. | Acetyltransferase family protein. | 0.500 |
| acs | adhE | CH53_1439 | CH53_3871 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.923 |
| acs | cobB-2 | CH53_1439 | CH53_4410 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Sir2 family protein; Belongs to the sirtuin family. Class III subfamily. | 0.460 |
| acs | nifJ | CH53_1439 | CH53_4046 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.974 |
| acs | pta-2 | CH53_1439 | CH53_392 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.931 |
| acs | yfiQ | CH53_1439 | CH53_2760 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetyltransferase family protein. | 0.527 |
| adhE | acs | CH53_3871 | CH53_1439 | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.923 |
| adhE | fadE | CH53_3871 | CH53_2783 | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | 0.422 |
| adhE | nifJ | CH53_3871 | CH53_4046 | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.978 |
| adhE | pta-2 | CH53_3871 | CH53_392 | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.957 |
| adhE | yfiQ | CH53_3871 | CH53_2760 | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | Acetyltransferase family protein. | 0.486 |
| cobB-2 | acs | CH53_4410 | CH53_1439 | Sir2 family protein; Belongs to the sirtuin family. Class III subfamily. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.460 |
| cobB-2 | pta-2 | CH53_4410 | CH53_392 | Sir2 family protein; Belongs to the sirtuin family. Class III subfamily. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.660 |
| cobB-2 | yfiQ | CH53_4410 | CH53_2760 | Sir2 family protein; Belongs to the sirtuin family. Class III subfamily. | Acetyltransferase family protein. | 0.536 |
| fadE | adhE | CH53_2783 | CH53_3871 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | Aldehyde dehydrogenase family protein; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family. | 0.422 |
| fadE | nifJ | CH53_2783 | CH53_4046 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.730 |
| fadE | yfiQ | CH53_2783 | CH53_2760 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | Acetyltransferase family protein. | 0.558 |
| nifJ | acs | CH53_4046 | CH53_1439 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.974 |