| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acs | fadE | CH53_1439 | CH53_2783 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | 0.482 |
| acs | maeB | CH53_1439 | CH53_551 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Malic enzyme, NAD binding domain protein. | 0.564 |
| acs | nifJ | CH53_1439 | CH53_4046 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.963 |
| acs | pta-2 | CH53_1439 | CH53_392 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.944 |
| acs | yfiQ | CH53_1439 | CH53_2760 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Acetyltransferase family protein. | 0.593 |
| agaR | yfiQ | CH53_238 | CH53_2760 | deoR-like helix-turn-helix domain protein. | Acetyltransferase family protein. | 0.503 |
| deoR_2 | yfiQ | CH53_213 | CH53_2760 | deoR-like helix-turn-helix domain protein. | Acetyltransferase family protein. | 0.503 |
| dhaM | nifJ | CH53_1148 | CH53_4046 | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.424 |
| dhaM | pta-2 | CH53_1148 | CH53_392 | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.446 |
| dhaM | yfiQ | CH53_1148 | CH53_2760 | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | Acetyltransferase family protein. | 0.515 |
| fadE | acs | CH53_2783 | CH53_1439 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.482 |
| fadE | nifJ | CH53_2783 | CH53_4046 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.592 |
| fadE | yfiQ | CH53_2783 | CH53_2760 | Hypothetical protein; acyl-CoA dehydrogenase, C-terminal domain protein. | Acetyltransferase family protein. | 0.550 |
| glcR_2 | yfiQ | CH53_3404 | CH53_2760 | deoR-like helix-turn-helix domain protein. | Acetyltransferase family protein. | 0.503 |
| glpR | yfiQ | CH53_1573 | CH53_2760 | Glycerol-3-phosphate regulon repressor. | Acetyltransferase family protein. | 0.503 |
| maeB | acs | CH53_551 | CH53_1439 | Malic enzyme, NAD binding domain protein. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.564 |
| maeB | nifJ | CH53_551 | CH53_4046 | Malic enzyme, NAD binding domain protein. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.964 |
| maeB | pta-2 | CH53_551 | CH53_392 | Malic enzyme, NAD binding domain protein. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.558 |
| maeB | yfiQ | CH53_551 | CH53_2760 | Malic enzyme, NAD binding domain protein. | Acetyltransferase family protein. | 0.513 |
| nifJ | acs | CH53_4046 | CH53_1439 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.963 |