| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_2060 | ycgJ | CH53_2060 | CH53_2812 | Hypothetical protein. | S-adenosyl-L-methionine-dependent methyltransferase family protein. | 0.441 |
| CH53_2813 | ycgJ | CH53_2813 | CH53_2812 | Hypothetical protein. | S-adenosyl-L-methionine-dependent methyltransferase family protein. | 0.421 |
| bioB | birA | CH53_3184 | CH53_2081 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.952 |
| bioB | ycgJ | CH53_3184 | CH53_2812 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | S-adenosyl-L-methionine-dependent methyltransferase family protein. | 0.491 |
| birA | bioB | CH53_2081 | CH53_3184 | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.952 |
| birA | ycgJ | CH53_2081 | CH53_2812 | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | S-adenosyl-L-methionine-dependent methyltransferase family protein. | 0.467 |
| pgaA | prn | CH53_3716 | CH53_637 | PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. | Autotrans_barl: outer membrane autotransporter barrel domain protein. | 0.549 |
| pgaA | ycgJ | CH53_3716 | CH53_2812 | PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. | S-adenosyl-L-methionine-dependent methyltransferase family protein. | 0.419 |
| pgaA | ydgC | CH53_3716 | CH53_3618 | PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. | Inner membrane protein ydgC. | 0.418 |
| prn | pgaA | CH53_637 | CH53_3716 | Autotrans_barl: outer membrane autotransporter barrel domain protein. | PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. | 0.549 |
| prn | ycgJ | CH53_637 | CH53_2812 | Autotrans_barl: outer membrane autotransporter barrel domain protein. | S-adenosyl-L-methionine-dependent methyltransferase family protein. | 0.445 |
| prn | ydgC | CH53_637 | CH53_3618 | Autotrans_barl: outer membrane autotransporter barrel domain protein. | Inner membrane protein ydgC. | 0.717 |
| ycgJ | CH53_2060 | CH53_2812 | CH53_2060 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Hypothetical protein. | 0.441 |
| ycgJ | CH53_2813 | CH53_2812 | CH53_2813 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Hypothetical protein. | 0.421 |
| ycgJ | bioB | CH53_2812 | CH53_3184 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.491 |
| ycgJ | birA | CH53_2812 | CH53_2081 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.467 |
| ycgJ | pgaA | CH53_2812 | CH53_3716 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | PGA_TPR_OMP: poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA. | 0.419 |
| ycgJ | prn | CH53_2812 | CH53_637 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Autotrans_barl: outer membrane autotransporter barrel domain protein. | 0.445 |
| ycgJ | ydgC | CH53_2812 | CH53_3618 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Inner membrane protein ydgC. | 0.504 |
| ycgJ | yycN | CH53_2812 | CH53_2811 | S-adenosyl-L-methionine-dependent methyltransferase family protein. | Acetyltransferase domain protein. | 0.492 |