Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
makGlucokinase family protein. (304 aa)    
Predicted Functional Partners:
fruA
FRU: PTS system, Fru family, IIB component domain protein.
    
 0.933
nagB
Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion.
    
 0.917
manA
manA: mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family.
  
 
 0.912
yicI
Glycosyl hydrolases 31 family protein; Belongs to the glycosyl hydrolase 31 family.
  
 
 0.910
xylA
xylose_isom_A: xylose isomerase; Belongs to the xylose isomerase family.
    
 0.908
pgi
Glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.908
glmS
Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.907
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.907
rpe-2
Rpe: ribulose-phosphate 3-epimerase.
  
 
 0.907
scrB
Sucrose-6-phosphate hydrolase family protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family.
  
 
 0.906
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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