| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| fruA | mak | CH53_232 | CH53_2818 | FRU: PTS system, Fru family, IIB component domain protein. | Glucokinase family protein. | 0.940 |
| fruA | manA | CH53_232 | CH53_3960 | FRU: PTS system, Fru family, IIB component domain protein. | manA: mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.674 |
| fruA | nagB | CH53_232 | CH53_3097 | FRU: PTS system, Fru family, IIB component domain protein. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.432 |
| fruA | pfkA | CH53_232 | CH53_1887 | FRU: PTS system, Fru family, IIB component domain protein. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.547 |
| fruA | pgi | CH53_232 | CH53_2139 | FRU: PTS system, Fru family, IIB component domain protein. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.546 |
| fruA | rpe-2 | CH53_232 | CH53_3037 | FRU: PTS system, Fru family, IIB component domain protein. | Rpe: ribulose-phosphate 3-epimerase. | 0.524 |
| fruA | scrB | CH53_232 | CH53_1138 | FRU: PTS system, Fru family, IIB component domain protein. | Sucrose-6-phosphate hydrolase family protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.451 |
| fruA | xylA | CH53_232 | CH53_1665 | FRU: PTS system, Fru family, IIB component domain protein. | xylose_isom_A: xylose isomerase; Belongs to the xylose isomerase family. | 0.940 |
| glmS | mak | CH53_1766 | CH53_2818 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucokinase family protein. | 0.908 |
| glmS | manA | CH53_1766 | CH53_3960 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | manA: mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.919 |
| glmS | nagB | CH53_1766 | CH53_3097 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.939 |
| glmS | pgi | CH53_1766 | CH53_2139 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.933 |
| mak | fruA | CH53_2818 | CH53_232 | Glucokinase family protein. | FRU: PTS system, Fru family, IIB component domain protein. | 0.940 |
| mak | glmS | CH53_2818 | CH53_1766 | Glucokinase family protein. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.908 |
| mak | manA | CH53_2818 | CH53_3960 | Glucokinase family protein. | manA: mannose-6-phosphate isomerase, class I; Belongs to the mannose-6-phosphate isomerase type 1 family. | 0.912 |
| mak | nagB | CH53_2818 | CH53_3097 | Glucokinase family protein. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.911 |
| mak | pfkA | CH53_2818 | CH53_1887 | Glucokinase family protein. | 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. | 0.909 |
| mak | pgi | CH53_2818 | CH53_2139 | Glucokinase family protein. | Glucose-6-phosphate isomerase; Belongs to the GPI family. | 0.910 |
| mak | rpe-2 | CH53_2818 | CH53_3037 | Glucokinase family protein. | Rpe: ribulose-phosphate 3-epimerase. | 0.908 |
| mak | scrB | CH53_2818 | CH53_1138 | Glucokinase family protein. | Sucrose-6-phosphate hydrolase family protein; Enables the bacterium to metabolize sucrose as a sole carbon source; Belongs to the glycosyl hydrolase 32 family. | 0.907 |