STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
CH53_2992GDSL-like Lipase/Acylhydrolase family protein. (426 aa)    
Predicted Functional Partners:
hlyD
type_I_hlyD: type I secretion membrane fusion, HlyD family protein.
  
   
 0.739
cry8Ca
Hypothetical protein; Delta endotoxin, N-terminal domain protein.
       0.566
prcA
Proconvertase P-domain protein.
   
  
 0.552
invG
type_III_yscC: type III secretion outer membrane pore, YscC/HrcC family.
  
  
 0.550
outI
Type II secretion system (T2SS), I family protein.
      
 0.514
CH53_2662
Type II secretion system (T2SS), K family protein.
      
 0.514
lapB
Tetratricopeptide repeat family protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.514
outO
Type IV leader peptidase family protein; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
      
 0.511
CH53_2456
Hypothetical protein; Transcriptional regulatory, C terminal family protein.
      
 0.509
lipA
Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
      
 0.508
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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