| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_1711 | rlpA | CH53_1711 | CH53_3062 | Hypothetical protein; Dipeptidyl peptidase IV (DPP IV) N-terminal region family protein. | Rare lipoA family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.578 |
| dacA | mrdA | CH53_3061 | CH53_3064 | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.961 |
| dacA | mrdB | CH53_3061 | CH53_3063 | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.624 |
| dacA | rlmH | CH53_3061 | CH53_3065 | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.622 |
| dacA | rlpA | CH53_3061 | CH53_3062 | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | Rare lipoA family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.529 |
| dacA | rsfS | CH53_3061 | CH53_3066 | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.450 |
| dacA | tolB | CH53_3061 | CH53_3155 | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.490 |
| mltD_2 | rlpA | CH53_767 | CH53_3062 | lysM domain protein. | Rare lipoA family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.513 |
| mltD_2 | yceG | CH53_767 | CH53_2 | lysM domain protein. | yceG-like family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.629 |
| mrdA | dacA | CH53_3064 | CH53_3061 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | 0.961 |
| mrdA | mrdB | CH53_3064 | CH53_3063 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.998 |
| mrdA | rlmH | CH53_3064 | CH53_3065 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.794 |
| mrdA | rlpA | CH53_3064 | CH53_3062 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Rare lipoA family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.806 |
| mrdA | rsfS | CH53_3064 | CH53_3066 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.671 |
| mrdA | tolB | CH53_3064 | CH53_3155 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane. | 0.583 |
| mrdA | yceG | CH53_3064 | CH53_2 | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | yceG-like family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.514 |
| mrdB | dacA | CH53_3063 | CH53_3061 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | D-alanyl-D-alanine carboxypeptidase dacA; Belongs to the peptidase S11 family. | 0.624 |
| mrdB | mrdA | CH53_3063 | CH53_3064 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.998 |
| mrdB | rlmH | CH53_3063 | CH53_3065 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | rRNA large subunit m3Psi methyltransferase RlmH; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.702 |
| mrdB | rlpA | CH53_3063 | CH53_3062 | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | Rare lipoA family protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.880 |