| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| crr | murQ | CH53_527 | CH53_1386 | Glucose-specific phosphotransferase enzyme IIA component. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | 0.907 |
| crr | murQ-2 | CH53_527 | CH53_673 | Glucose-specific phosphotransferase enzyme IIA component. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | 0.907 |
| crr | nagA-2 | CH53_527 | CH53_3096 | Glucose-specific phosphotransferase enzyme IIA component. | nagA: N-acetylglucosamine-6-phosphate deacetylase. | 0.932 |
| crr | nagB | CH53_527 | CH53_3097 | Glucose-specific phosphotransferase enzyme IIA component. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.474 |
| crr | nagE | CH53_527 | CH53_3098 | Glucose-specific phosphotransferase enzyme IIA component. | PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component. | 0.978 |
| crr | nagK | CH53_527 | CH53_4411 | Glucose-specific phosphotransferase enzyme IIA component. | Glucokinase family protein; Catalyzes the phosphorylation of N-acetyl-D-glucosamine (GlcNAc) derived from cell-wall degradation, yielding GlcNAc-6-P. | 0.903 |
| crr | nanE | CH53_527 | CH53_2498 | Glucose-specific phosphotransferase enzyme IIA component. | Nitronate monooxygenase family protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P). | 0.904 |
| glmM | glmS | CH53_1285 | CH53_1766 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.970 |
| glmM | nagA-2 | CH53_1285 | CH53_3096 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | nagA: N-acetylglucosamine-6-phosphate deacetylase. | 0.912 |
| glmM | nagB | CH53_1285 | CH53_3097 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.930 |
| glmS | glmM | CH53_1766 | CH53_1285 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.970 |
| glmS | nagA-2 | CH53_1766 | CH53_3096 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | nagA: N-acetylglucosamine-6-phosphate deacetylase. | 0.919 |
| glmS | nagB | CH53_1766 | CH53_3097 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.937 |
| glmS | nagE | CH53_1766 | CH53_3098 | Glutamine-fructose-6-phosphate transaminase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component. | 0.408 |
| mlc_2 | nagA-2 | CH53_3095 | CH53_3096 | marR family protein. | nagA: N-acetylglucosamine-6-phosphate deacetylase. | 0.827 |
| mlc_2 | nagB | CH53_3095 | CH53_3097 | marR family protein. | Glucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion. | 0.787 |
| mlc_2 | nagE | CH53_3095 | CH53_3098 | marR family protein. | PTS-II-BC-nag: PTS system, N-acetylglucosamine-specific IIBC component. | 0.908 |
| murQ | crr | CH53_1386 | CH53_527 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | Glucose-specific phosphotransferase enzyme IIA component. | 0.907 |
| murQ | murQ-2 | CH53_1386 | CH53_673 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | 0.902 |
| murQ | nagA-2 | CH53_1386 | CH53_3096 | N-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. Together with AnmK, is also required for the utilization of anhydro-N-acetylmuramic acid (anhMurNAc) either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily. | nagA: N-acetylglucosamine-6-phosphate deacetylase. | 0.941 |