| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceB | aceF | CH53_2121 | CH53_994 | malate_syn_A: malate synthase A. | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.914 |
| aceB | acs | CH53_2121 | CH53_1439 | malate_syn_A: malate synthase A. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.943 |
| aceB | fumA | CH53_2121 | CH53_856 | malate_syn_A: malate synthase A. | Hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.929 |
| aceB | fumB | CH53_2121 | CH53_306 | malate_syn_A: malate synthase A. | Hydrolyase, tartrate beta subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.929 |
| aceB | fumC | CH53_2121 | CH53_3961 | malate_syn_A: malate synthase A. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.922 |
| aceB | gltA | CH53_2121 | CH53_3137 | malate_syn_A: malate synthase A. | cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family. | 0.965 |
| aceB | mdh | CH53_2121 | CH53_1302 | malate_syn_A: malate synthase A. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.940 |
| aceB | nifJ | CH53_2121 | CH53_4046 | malate_syn_A: malate synthase A. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.952 |
| aceF | aceB | CH53_994 | CH53_2121 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | malate_syn_A: malate synthase A. | 0.914 |
| aceF | acnB | CH53_994 | CH53_990 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | acnB: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 0.536 |
| aceF | acs | CH53_994 | CH53_1439 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.917 |
| aceF | fumC | CH53_994 | CH53_3961 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.512 |
| aceF | gltA | CH53_994 | CH53_3137 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | cit_synth_I: citrate (Si)-synthase; Belongs to the citrate synthase family. | 0.982 |
| aceF | mdh | CH53_994 | CH53_1302 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. | 0.477 |
| aceF | nifJ | CH53_994 | CH53_4046 | Dihydrolipoyllysine-residue acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.957 |
| acnA | acnB | CH53_3911 | CH53_990 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | acnB: aconitate hydratase 2; Belongs to the aconitase/IPM isomerase family. | 0.955 |
| acnA | acs | CH53_3911 | CH53_1439 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. Acs undergoes a two-step reaction. In the first half reaction, Acs combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.446 |
| acnA | fumA | CH53_3911 | CH53_856 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Hydrolyase, tartrate alpha subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.734 |
| acnA | fumB | CH53_3911 | CH53_306 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Hydrolyase, tartrate beta subunit/fumarate, Fe-S type domain protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.734 |
| acnA | fumC | CH53_3911 | CH53_3961 | Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. | Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. | 0.960 |