STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
zitBCDF: cation diffusion facilitator transporter family protein. (309 aa)    
Predicted Functional Partners:
bvgS_2
His Kinase A domain protein.
     
 0.712
copA_3
ATPase-IB1_Cu: copper-translocating P-type ATPase.
  
  
 0.706
cadA
ATPase-IB2_Cd: cadmium-translocating P-type ATPase.
  
  
 0.679
bvgA_2
Bacterial regulatory s, luxR family protein.
       0.648
zntR
zntR: Zn(II)-responsive transcriptional regulator.
     
 0.626
cusA_2
2A0601: heavy metal efflux pump, CzcA family protein; Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.
 
   
 0.624
zntB
corA-like Mg2+ transporter family protein.
 
   
 0.621
mntH
Manganese transport protein mntH; H(+)-stimulated, divalent metal cation uptake system. Belongs to the NRAMP family.
  
 
 0.473
metJ
Met Apo-repressor, MetJ family protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
      
 0.438
lsrK
Autoinducer 2 kinase LsrK; Catalyzes the phosphorylation of autoinducer-2 (AI-2) to phospho-AI-2, which subsequently inactivates the transcriptional regulator LsrR and leads to the transcription of the lsr operon. Phosphorylates the ring-open form of (S)-4,5-dihydroxypentane-2,3-dione (DPD), which is the precursor to all AI-2 signaling molecules, at the C5 position.
  
    0.414
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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