Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
acnRBacterial regulatory s, tetR family protein. (236 aa)    
Predicted Functional Partners:
macA_2
RND_mfp: efflux transporter, RND family, MFP subunit.
 
  
 0.840
ccmA-8
ccmA: heme ABC exporter, ATP-binding protein CcmA.
 
    0.792
ybhS
ABC-2 type transporter family protein.
 
  
 0.750
ybhR
Inner membrane transport permease ybhR.
 
  
 0.720
CH53_2976
Antirestriction family protein.
  
     0.499
leuO
Putative HTH-type transcriptional regulator leuO; Belongs to the LysR transcriptional regulatory family.
  
 
   0.417
rcsA_2
Bacterial regulatory s, luxR family protein.
  
   
 0.412
gyrI
gyrI-like small molecule binding domain protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell.
  
     0.405
yhaH
Hypothetical protein.
  
     0.402
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.