STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpD_1Glycosyl transferase family, helical bundle domain protein. (319 aa)    
Predicted Functional Partners:
trpE
trpE_proteo: anthranilate synthase component I.
 
 
 0.890
pabB
pabB: aminodeoxychorismate synthase, component I.
 
 
 0.883
trpC
Indole-3-glycerol phosphate synthase family protein; Belongs to the TrpC family.
 
  
 0.774
trpA
Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.770
trpB
Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
 
  
 0.769
trpG
Anthranilate synthase component II.
 
  
 0.720
pabA
trpG_papA: glutamine amidotransferase of anthranilate synthase/aminodeoxychorismate synthase family protein.
 
  
 0.699
thrA
Asp_kinase: aspartate kinase domain protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
   
  
 0.581
metL
Homoserine dehydrogenase, NAD binding domain protein; In the C-terminal section; belongs to the homoserine dehydrogenase family.
   
  
 0.581
hisE
histidine_hisI: phosphoribosyl-ATP diphosphatase; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.544
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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