STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hyfGNickel-dependent hydrogenase family protein. (606 aa)    
Predicted Functional Partners:
hyfI
NADH ubiquinone oxidoreductase, 20 Kd subunit.
 
 0.999
hyfF
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein.
 
 
 0.999
hyfB
Hydrogenase-4 component B.
 
 
 0.999
hyfH
4Fe-4S dicluster domain protein.
 
 
 0.998
hyfE
Hydrogenase-4 component E.
 
  
 0.998
hyfC
Hydrogenase-4 component C.
 
 
 0.998
hyfD
NADH-Ubiquinone/plastoquinone (complex I), various chains family protein.
 
 
 0.987
hyfA
4Fe-4S dicluster domain protein.
 
 
 0.983
nuoI
NADH-quinone oxidoreductase, chain I family protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
 
 0.983
fdhF_2
Fdh-alpha: formate dehydrogenase, alpha subunit; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
 
 
 0.977
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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