STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiKSirohydrochlorin cobaltochelatase; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (264 aa)    
Predicted Functional Partners:
cobI
cobI_cbiL: precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
 0.999
cobM
cobM_cbiF: precorrin-4 C11-methyltransferase.
  
 0.995
cbiG
Cobalamin synthesis G family protein.
 
  
 0.991
cobK
Precor6x_red: precorrin-6x reductase.
 
  
 0.989
cbiD
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.982
cbiH
cobalt-precorrin-3B C(17)-methyltransferase.
 
  
 0.978
cbiC
cobalt-precorrin-8X methylmutase.
 
  
 0.964
cbiE
cbiE: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit.
 
  
 0.964
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
 
 
 0.954
cbiT
cbiT: precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit.
 
    0.954
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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