Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
oprF_2ompA family protein. (575 aa)    
Predicted Functional Partners:
CH53_3410
IV_VI_DotU: type IV/VI secretion system, DotU family domain protein.
 
  
 0.940
hcp3_1
VI_effect_Hcp1: type VI secretion system effector, Hcp1 family protein.
 
    0.928
CH53_3409
Hypothetical protein.
 
  
 0.868
CH53_3422
Intracellular multiplication and macrophage-killing family protein.
 
  
 0.755
CH53_3427
Lysozyme family protein; Gene 25-like.
  
  
 0.755
CH53_3423
impA-related N-terminal family protein.
  
     0.736
CH53_3426
Type VI secretion lipofamily protein.
  
   
 0.724
CH53_906
VI_effect_Hcp1: type VI secretion system effector, Hcp1 family protein.
 
    0.701
tolB
Tol-Pal system beta propeller repeat protein TolB; Part of the Tol-Pal system, which plays a role in outer membrane invagination during cell division and is important for maintaining outer membrane integrity. TolB occupies a key intermediary position in the Tol-Pal system because it communicates directly with both membrane-embedded components, Pal in the outer membrane and TolA in the inner membrane.
  
 
 0.691
ompA
Outer membrane protein A; Belongs to the outer membrane OOP (TC 1.B.6) superfamily.
  
 
 0.673
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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