Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (603 aa)    
Predicted Functional Partners:
eda
Eda: 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase family protein.
 
 
 0.993
gntK_2
Therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family protein.
  
 
 0.942
gntK_1
Therm_gnt_kin: carbohydrate kinase, thermoresistant glucokinase family protein.
  
 
 0.935
gnd
6-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.928
kdgK
pfkB carbohydrate kinase family protein.
 
  
 0.919
zwf
Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.918
pgl
Lactonase, 7-bladed beta-propeller family protein; Catalyzes the hydrolysis of 6-phosphogluconolactone to 6- phosphogluconate.
     
 0.901
glk
Glk: glucokinase; Belongs to the bacterial glucokinase family.
 
  
 0.867
gltB
Glutamine amidotransferases class-II family protein.
  
  
 0.777
CH53_361
Hypothetical protein; Belongs to the UPF0303 family.
       0.773
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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