| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CH53_159 | CH53_3174 | CH53_159 | CH53_3174 | ycaO-type kinase domain protein. | CAAX protease self-immunity family protein. | 0.786 |
| CH53_159 | yadH | CH53_159 | CH53_980 | ycaO-type kinase domain protein. | Inner membrane transport permease yadH. | 0.548 |
| CH53_159 | ybhR | CH53_159 | CH53_3198 | ycaO-type kinase domain protein. | Inner membrane transport permease ybhR. | 0.548 |
| CH53_159 | ybhS | CH53_159 | CH53_3199 | ycaO-type kinase domain protein. | ABC-2 type transporter family protein. | 0.548 |
| CH53_159 | ydjA | CH53_159 | CH53_3853 | ycaO-type kinase domain protein. | Putative NAD(P)H nitroreductase ydjA. | 0.761 |
| CH53_3174 | CH53_159 | CH53_3174 | CH53_159 | CAAX protease self-immunity family protein. | ycaO-type kinase domain protein. | 0.786 |
| CH53_3174 | yadH | CH53_3174 | CH53_980 | CAAX protease self-immunity family protein. | Inner membrane transport permease yadH. | 0.500 |
| CH53_3174 | ybhR | CH53_3174 | CH53_3198 | CAAX protease self-immunity family protein. | Inner membrane transport permease ybhR. | 0.500 |
| CH53_3174 | ybhS | CH53_3174 | CH53_3199 | CAAX protease self-immunity family protein. | ABC-2 type transporter family protein. | 0.500 |
| CH53_3174 | ydjA | CH53_3174 | CH53_3853 | CAAX protease self-immunity family protein. | Putative NAD(P)H nitroreductase ydjA. | 0.606 |
| birA | tadA | CH53_2081 | CH53_670 | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.914 |
| birA | ydjA | CH53_2081 | CH53_3853 | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | Putative NAD(P)H nitroreductase ydjA. | 0.679 |
| fadD | ydjA | CH53_3819 | CH53_3853 | AMP-binding enzyme family protein. | Putative NAD(P)H nitroreductase ydjA. | 0.644 |
| metH | nifJ | CH53_2131 | CH53_4046 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | 0.731 |
| metH | ydjA | CH53_2131 | CH53_3853 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Putative NAD(P)H nitroreductase ydjA. | 0.630 |
| nifJ | metH | CH53_4046 | CH53_2131 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.731 |
| nifJ | ydjA | CH53_4046 | CH53_3853 | Pyruvate:ferredoxin (flavodoxin) oxidoreductase; pyruv_ox_red: pyruvate:ferredoxin (flavodoxin) oxidoreductase. | Putative NAD(P)H nitroreductase ydjA. | 0.697 |
| tadA | birA | CH53_670 | CH53_2081 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | Bifunctional protein BirA; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.914 |
| tadA | ydjA | CH53_670 | CH53_3853 | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | Putative NAD(P)H nitroreductase ydjA. | 0.610 |
| yadH | CH53_159 | CH53_980 | CH53_159 | Inner membrane transport permease yadH. | ycaO-type kinase domain protein. | 0.548 |