STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hlyDtype_I_hlyD: type I secretion membrane fusion, HlyD family protein. (464 aa)    
Predicted Functional Partners:
apxIB_1
type_I_sec_HlyB: type I secretion system ATPase family protein.
 
 0.972
apxIB_2
type_I_sec_HlyB: type I secretion system ATPase family protein.
 
 0.971
prtA
Secreted protease A.
 
  
 0.793
prsD
type_I_sec_PrtD: type I secretion system ATPase family protein.
  
 0.695
hasD
type_I_sec_PrtD: type I secretion system ATPase family protein.
  
 0.680
macB_5
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.643
macB_4
ABC transporter family protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.643
macB_1
ABC transporter family protein; Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner. Belongs to the ABC transporter superfamily. Macrolide exporter (TC 3.A.1.122) family.
  
 
 0.643
ompC
Outer membrane protein C; Belongs to the Gram-negative porin family.
      
 0.635
tolC_2
type_I_sec_TolC: type I secretion outer membrane, TolC family protein.
 
 
 0.599
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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