Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
gyrIgyrI-like small molecule binding domain protein; Inhibits the supercoiling activity of DNA gyrase. Acts by inhibiting DNA gyrase at an early step, prior to (or at the step of) binding of DNA by the gyrase. It protects cells against toxins that target DNA gyrase, by inhibiting activity of these toxins and reducing the formation of lethal double-strand breaks in the cell. (157 aa)    
Predicted Functional Partners:
ihfA
Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
   
  
 0.520
CH53_4020
Hypothetical protein.
       0.518
CH53_2270
Radical SAM superfamily protein.
  
    0.502
CH53_703
Hypothetical protein.
  
     0.482
bcsE
cellulose_bcsE: cellulose biosynthesis protein BcsE.
  
     0.467
CH53_3100
Outer membrane porin, OprD family protein.
  
     0.467
CH53_634
beta/Gamma crystallin family protein.
  
    0.463
esaI
Acyl-homoserine-lactone synthase.
  
     0.448
lacZ_2
Glycosyl hydrolases 2 family protein; Belongs to the glycosyl hydrolase 2 family.
  
     0.429
yaeP
Hypothetical protein.
  
     0.417
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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