| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dhaM | fryA | CH53_1148 | CH53_332 | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | PEP-utilizing enzyme, mobile domain protein. | 0.992 |
| dhaM | purR | CH53_1148 | CH53_4099 | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.545 |
| fryA | dhaM | CH53_332 | CH53_1148 | PEP-utilizing enzyme, mobile domain protein. | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | 0.992 |
| fryA | gltB | CH53_332 | CH53_2269 | PEP-utilizing enzyme, mobile domain protein. | Glutamine amidotransferases class-II family protein. | 0.423 |
| fryA | purR | CH53_332 | CH53_4099 | PEP-utilizing enzyme, mobile domain protein. | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.586 |
| gltB | fryA | CH53_2269 | CH53_332 | Glutamine amidotransferases class-II family protein. | PEP-utilizing enzyme, mobile domain protein. | 0.423 |
| gltB | purR | CH53_2269 | CH53_4099 | Glutamine amidotransferases class-II family protein. | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.661 |
| purR | dhaM | CH53_4099 | CH53_1148 | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | PTS-dependent dihydroxyacetone kinase, phosphotransferase subunit dhaM; Belongs to the PEP-utilizing enzyme family. | 0.545 |
| purR | fryA | CH53_4099 | CH53_332 | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | PEP-utilizing enzyme, mobile domain protein. | 0.586 |
| purR | gltB | CH53_4099 | CH53_2269 | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Glutamine amidotransferases class-II family protein. | 0.661 |
| purR | rbsD | CH53_4099 | CH53_1786 | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | rbsD / FucU transport family protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. | 0.664 |
| purR | udk | CH53_4099 | CH53_3302 | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | Udk: uridine kinase. | 0.590 |
| rbsD | purR | CH53_1786 | CH53_4099 | rbsD / FucU transport family protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.664 |
| rbsD | udk | CH53_1786 | CH53_3302 | rbsD / FucU transport family protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. | Udk: uridine kinase. | 0.590 |
| udk | purR | CH53_3302 | CH53_4099 | Udk: uridine kinase. | Bacterial regulatory s, lacI family protein; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.590 |
| udk | rbsD | CH53_3302 | CH53_1786 | Udk: uridine kinase. | rbsD / FucU transport family protein; Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose. | 0.590 |