| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaX | holB | CH53_2900 | CH53_4426 | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | Hypothetical protein; DNA polymerase III, delta subunit, C terminal family protein. | 0.997 |
| dnaX | lepA | CH53_2900 | CH53_682 | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.425 |
| dnaX | metG | CH53_2900 | CH53_3300 | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.803 |
| dnaX | tsaD | CH53_2900 | CH53_2328 | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.493 |
| dnaX | ycfH | CH53_2900 | CH53_4425 | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | Hydrolase, TatD family protein. | 0.440 |
| holB | dnaX | CH53_4426 | CH53_2900 | Hypothetical protein; DNA polymerase III, delta subunit, C terminal family protein. | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | 0.997 |
| holB | metG | CH53_4426 | CH53_3300 | Hypothetical protein; DNA polymerase III, delta subunit, C terminal family protein. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.487 |
| holB | yceG | CH53_4426 | CH53_2 | Hypothetical protein; DNA polymerase III, delta subunit, C terminal family protein. | yceG-like family protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.552 |
| holB | ycfH | CH53_4426 | CH53_4425 | Hypothetical protein; DNA polymerase III, delta subunit, C terminal family protein. | Hydrolase, TatD family protein. | 0.606 |
| lepA | dnaX | CH53_682 | CH53_2900 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | 0.425 |
| lepA | metG | CH53_682 | CH53_3300 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.619 |
| lepA | rpsB | CH53_682 | CH53_2720 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | rpsB_bact: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.971 |
| lepA | tsaD | CH53_682 | CH53_2328 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.658 |
| lepA | ycfH | CH53_682 | CH53_4425 | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Hydrolase, TatD family protein. | 0.499 |
| metG | dnaX | CH53_3300 | CH53_2900 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | dnaX_nterm: DNA polymerase III, subunit gamma and tau. | 0.803 |
| metG | holB | CH53_3300 | CH53_4426 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Hypothetical protein; DNA polymerase III, delta subunit, C terminal family protein. | 0.487 |
| metG | lepA | CH53_3300 | CH53_682 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Elongation factor 4; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.619 |
| metG | rpsB | CH53_3300 | CH53_2720 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | rpsB_bact: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family. | 0.758 |
| metG | tsaD | CH53_3300 | CH53_2328 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.725 |
| metG | ycfH | CH53_3300 | CH53_4425 | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | Hydrolase, TatD family protein. | 0.427 |