| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| engA | era | CH53_625 | CH53_679 | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.786 |
| engA | rsmA | CH53_625 | CH53_1058 | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.414 |
| era | engA | CH53_679 | CH53_625 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosome-associated GTPase EngA; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family. | 0.786 |
| era | fabD | CH53_679 | CH53_7 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | fabD: malonyl CoA-acyl carrier protein transacylase. | 0.733 |
| era | recO | CH53_679 | CH53_678 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | 0.923 |
| era | rnc | CH53_679 | CH53_680 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | RNaseIII: ribonuclease III. | 0.889 |
| era | rpsF | CH53_679 | CH53_1325 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.815 |
| era | rpsG | CH53_679 | CH53_1494 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.798 |
| era | rpsI | CH53_679 | CH53_2264 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.740 |
| era | rpsP | CH53_679 | CH53_808 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | S16: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.787 |
| era | rsmA | CH53_679 | CH53_1058 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Ribosomal RNA small subunit methyltransferase A; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.764 |
| era | ybeY | CH53_679 | CH53_3080 | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Putative rRNA maturation factor YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.829 |
| fabD | era | CH53_7 | CH53_679 | fabD: malonyl CoA-acyl carrier protein transacylase. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.733 |
| fabD | rpsF | CH53_7 | CH53_1325 | fabD: malonyl CoA-acyl carrier protein transacylase. | Ribosomal protein S6; Binds together with S18 to 16S ribosomal RNA. | 0.550 |
| fabD | rpsG | CH53_7 | CH53_1494 | fabD: malonyl CoA-acyl carrier protein transacylase. | Ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. | 0.550 |
| fabD | rpsI | CH53_7 | CH53_2264 | fabD: malonyl CoA-acyl carrier protein transacylase. | 30S ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family. | 0.413 |
| fabD | rpsP | CH53_7 | CH53_808 | fabD: malonyl CoA-acyl carrier protein transacylase. | S16: ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family. | 0.828 |
| recO | era | CH53_678 | CH53_679 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.923 |
| recO | rnc | CH53_678 | CH53_680 | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. | RNaseIII: ribonuclease III. | 0.809 |
| rnc | era | CH53_680 | CH53_679 | RNaseIII: ribonuclease III. | GTP-binding protein Era; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.889 |
