Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
chbGydjC-like family protein; Involved in the degradation of chitin. ChbG is essential for growth on the acetylated chitooligosaccharides chitobiose and chitotriose but is dispensable for growth on cellobiose and chitosan dimer, the deacetylated form of chitobiose. Deacetylation of chitobiose-6-P and chitotriose-6-P is necessary for both the activation of the chb promoter by the regulatory protein ChbR and the hydrolysis of phosphorylated beta-glucosides by the phospho-beta-glucosidase ChbF. Catalyzes the removal of only one acetyl group from chitobiose-6-P to yield monoacetylchitobiose-6- [...] (253 aa)    
Predicted Functional Partners:
chbR
HTH-type transcriptional regulator ChbR.
 
   
 0.927
chbF
Hypothetical protein; Family 4 glycosyl hydrolase C-terminal domain protein.
 
 
 0.830
celB
PTS system, cellobiose-specific IIC component; The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane.
 
   
 0.812
chbB
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIB component.
 
   
 0.777
chbA-2
N,N'-diacetylchitobiose-specific phosphotransferase enzyme IIA component.
 
   
 0.767
bglA
Glycosyl hydrolase 1 family protein; Belongs to the glycosyl hydrolase 1 family.
  
 
 0.604
gmuD_2
Glycosyl hydrolase 1 family protein; Belongs to the glycosyl hydrolase 1 family.
 
  
 0.600
CH53_3100
Outer membrane porin, OprD family protein.
  
   
 0.594
CH53_710
flxA-like family protein.
       0.572
arnT
Dolichyl-phosphate-mannose-mannosyltransferase family protein; Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Belongs to the glycosyltransferase 83 family.
 
  
 0.535
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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