Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ureFureF family protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. (228 aa)    
Predicted Functional Partners:
ureD
ureD urease accessory family protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter.
 
 
 0.997
ureC
Urease_alph: urease, alpha subunit.
 
 
 0.994
ureE
Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family.
 
  
 0.991
yut
Urea_trans_yut: urea transporter.
 
   
 0.963
ureG
Urease accessory protein UreG; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG.
 
 
 0.959
ureA
Urease subunit gamma; Belongs to the urease gamma subunit family.
 
 
 0.950
ureB
Urease subunit beta; Belongs to the urease beta subunit family.
 
 
 0.946
hypB
hypB: hydrogenase accessory protein HypB.
  
 
 0.645
hoxN_2
Nico: transition metal uptake transporter, Ni2+-Co2+ transporter family protein; Belongs to the NiCoT transporter (TC 2.A.52) family.
     
 0.422
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
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