Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CH53_81Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase family protein. (143 aa)    
Predicted Functional Partners:
CH53_83
Ant_ant_sig: anti-anti-sigma factor family protein; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.997
cheY_2
Stage II sporulation E family protein.
 
 
 0.989
barA_2
Sensory box protein.
 
  
 0.958
fliA
RNA polymerase sigma factor for flagellar operon; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily.
  
 
 0.918
bvgS_2
His Kinase A domain protein.
 
  
 0.910
motA
motA1: flagellar motor stator protein MotA.
   
    0.883
flgB
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.883
flgH
Flagellar L-ring family protein; Assembles around the rod to form the L-ring and probably protects the motor/basal body from shearing forces during rotation.
   
    0.883
flgK
flgK_ends: flagellar hook-associated protein FlgK.
   
    0.883
fliG
Flagellar motor switch protein FliG; FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation.
   
    0.883
Your Current Organism:
Yersinia intermedia
NCBI taxonomy Id: 631
Other names: ATCC 29909, CCUG 11292, CIP 80.28, DSM 18517, JCM 7579, NCTC 11469, Y. intermedia, strain 3953, strain Bottone 48, strain Chester 48
Server load: low (26%) [HD]