STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIC23336.1Putative transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family. (118 aa)    
Predicted Functional Partners:
EIC23337.1
PAS domain S-box; PFAM: Response regulator receiver domain; PAS fold; TIGRFAM: PAS domain S-box.
       0.600
speE
Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
       0.587
EIC23334.1
Hypothetical protein.
       0.559
birA
birA, biotin-(acetyl-CoA-carboxylase) ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.445
EIC23338.1
PFAM: Response regulator receiver domain; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase; His Kinase A (phosphoacceptor) domain.
       0.443
EIC21783.1
Putative transcriptional regulator; PFAM: Bacterial regulatory protein, arsR family.
  
     0.438
EIC20339.1
Putative ATPase/kinase involved in NAD metabolism; TIGRFAM: nicotinamide-nucleotide adenylyltransferase, NadR type.
   
 
  0.432
cobB
NAD-dependent protein deacetylase, SIR2 family; PFAM: Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
 
  0.404
Your Current Organism:
Thiorhodovibrio sp. 970
NCBI taxonomy Id: 631362
Other names: T. sp. 970
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.