STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EIC22111.1Putative ATPase (AAA+ superfamily); PFAM: Protein of unknown function (DUF815). (293 aa)    
Predicted Functional Partners:
EIC22112.1
PFAM: ABC transporter; TIGRFAM: ATP-binding cassette protein, ChvD family.
       0.782
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
   0.561
EIC19344.1
PFAM: Prephenate dehydrogenase.
  
     0.531
hisZ
ATP phosphoribosyltransferase, regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
  
     0.487
EIC22109.1
Putative glutamine amidotransferase; PFAM: Peptidase C26.
       0.475
EIC22110.1
PFAM: Putative amidoligase enzyme.
       0.475
EIC21403.1
PFAM: ACT domain; Small subunit of acetolactate synthase; TIGRFAM: acetolactate synthase, small subunit.
 
     0.434
argA
Amino-acid N-acetyltransferase; PFAM: Acetyltransferase (GNAT) family; Amino acid kinase family; TIGRFAM: amino-acid N-acetyltransferase; Belongs to the acetyltransferase family. ArgA subfamily.
 
     0.404
Your Current Organism:
Thiorhodovibrio sp. 970
NCBI taxonomy Id: 631362
Other names: T. sp. 970
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