node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIC22239.1 | EIC22318.1 | Thi970DRAFT_02492 | Thi970DRAFT_02571 | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.441 |
EIC22239.1 | EIC22319.1 | Thi970DRAFT_02492 | Thi970DRAFT_02572 | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | PFAM: NAD dependent epimerase/dehydratase family. | 0.890 |
EIC22239.1 | EIC22320.1 | Thi970DRAFT_02492 | Thi970DRAFT_02573 | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain. | 0.886 |
EIC22239.1 | EIC22321.1 | Thi970DRAFT_02492 | Thi970DRAFT_02574 | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | Putative phosphatase; Manually curated. | 0.448 |
EIC22239.1 | EIC22323.1 | Thi970DRAFT_02492 | Thi970DRAFT_02576 | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | Hypothetical protein. | 0.545 |
EIC22239.1 | glyA | Thi970DRAFT_02492 | Thi970DRAFT_04939 | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.927 |
EIC22318.1 | EIC22239.1 | Thi970DRAFT_02571 | Thi970DRAFT_02492 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | 0.441 |
EIC22318.1 | EIC22319.1 | Thi970DRAFT_02571 | Thi970DRAFT_02572 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | PFAM: NAD dependent epimerase/dehydratase family. | 0.896 |
EIC22318.1 | EIC22320.1 | Thi970DRAFT_02571 | Thi970DRAFT_02573 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain. | 0.685 |
EIC22318.1 | EIC22321.1 | Thi970DRAFT_02571 | Thi970DRAFT_02574 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Putative phosphatase; Manually curated. | 0.825 |
EIC22318.1 | EIC22322.1 | Thi970DRAFT_02571 | Thi970DRAFT_02575 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family. | 0.738 |
EIC22318.1 | EIC22323.1 | Thi970DRAFT_02571 | Thi970DRAFT_02576 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Hypothetical protein. | 0.644 |
EIC22318.1 | EIC22324.1 | Thi970DRAFT_02571 | Thi970DRAFT_02577 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | CMP-2-keto-3-deoxyoctulosonic acid synthetase; PFAM: Cytidylyltransferase; TIGRFAM: 3-deoxy-D-manno-octulosonate cytidylyltransferase. | 0.643 |
EIC22318.1 | glyA | Thi970DRAFT_02571 | Thi970DRAFT_04939 | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.543 |
EIC22319.1 | EIC22239.1 | Thi970DRAFT_02572 | Thi970DRAFT_02492 | PFAM: NAD dependent epimerase/dehydratase family. | Polyketide synthase family protein; PFAM: Phosphopantetheine attachment site; Acyl transferase domain; 2-nitropropane dioxygenase; KR domain; Beta-ketoacyl synthase, N-terminal domain; Beta-ketoacyl synthase, C-terminal domain; TIGRFAM: polyketide-type polyunsaturated fatty acid synthase PfaA. | 0.890 |
EIC22319.1 | EIC22318.1 | Thi970DRAFT_02572 | Thi970DRAFT_02571 | PFAM: NAD dependent epimerase/dehydratase family. | Lactate dehydrogenase-like oxidoreductase; PFAM: D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain; D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain. | 0.896 |
EIC22319.1 | EIC22320.1 | Thi970DRAFT_02572 | Thi970DRAFT_02573 | PFAM: NAD dependent epimerase/dehydratase family. | Methylase involved in ubiquinone/menaquinone biosynthesis; PFAM: Methyltransferase domain. | 0.681 |
EIC22319.1 | EIC22321.1 | Thi970DRAFT_02572 | Thi970DRAFT_02574 | PFAM: NAD dependent epimerase/dehydratase family. | Putative phosphatase; Manually curated. | 0.970 |
EIC22319.1 | EIC22322.1 | Thi970DRAFT_02572 | Thi970DRAFT_02575 | PFAM: NAD dependent epimerase/dehydratase family. | 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; PFAM: HpcH/HpaI aldolase/citrate lyase family; Belongs to the HpcH/HpaI aldolase family. | 0.768 |
EIC22319.1 | EIC22323.1 | Thi970DRAFT_02572 | Thi970DRAFT_02576 | PFAM: NAD dependent epimerase/dehydratase family. | Hypothetical protein. | 0.727 |