node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIC19674.1 | EIC22902.1 | Thi970DRAFT_03264 | Thi970DRAFT_00541 | Hypothetical protein; Manually curated. | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.996 |
EIC19674.1 | EIC24021.1 | Thi970DRAFT_03264 | Thi970DRAFT_00162 | Hypothetical protein; Manually curated. | DNA-directed RNA polymerase, beta subunit/140 kD subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb2, domain 6; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb2, domain 7. | 0.957 |
EIC19674.1 | pheT | Thi970DRAFT_03264 | Thi970DRAFT_04622 | Hypothetical protein; Manually curated. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.986 |
EIC19674.1 | purL | Thi970DRAFT_03264 | Thi970DRAFT_03136 | Hypothetical protein; Manually curated. | Phosphoribosylformylglycinamidine synthase, single chain form; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.942 |
EIC19674.1 | secD | Thi970DRAFT_03264 | Thi970DRAFT_03858 | Hypothetical protein; Manually curated. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.972 |
EIC19674.1 | secE | Thi970DRAFT_03264 | Thi970DRAFT_01943 | Hypothetical protein; Manually curated. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.995 |
EIC19674.1 | secF | Thi970DRAFT_03264 | Thi970DRAFT_03859 | Hypothetical protein; Manually curated. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.972 |
EIC19674.1 | secY | Thi970DRAFT_03264 | Thi970DRAFT_01977 | Hypothetical protein; Manually curated. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.995 |
EIC19674.1 | yajC | Thi970DRAFT_03264 | Thi970DRAFT_03857 | Hypothetical protein; Manually curated. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.991 |
EIC19674.1 | yidC | Thi970DRAFT_03264 | Thi970DRAFT_02782 | Hypothetical protein; Manually curated. | Membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.998 |
EIC22902.1 | EIC19674.1 | Thi970DRAFT_00541 | Thi970DRAFT_03264 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Hypothetical protein; Manually curated. | 0.996 |
EIC22902.1 | pheT | Thi970DRAFT_00541 | Thi970DRAFT_04622 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.496 |
EIC22902.1 | secD | Thi970DRAFT_00541 | Thi970DRAFT_03858 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.983 |
EIC22902.1 | secE | Thi970DRAFT_00541 | Thi970DRAFT_01943 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecE subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.998 |
EIC22902.1 | secF | Thi970DRAFT_00541 | Thi970DRAFT_03859 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein-export membrane protein, SecD/SecF family; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.927 |
EIC22902.1 | secY | Thi970DRAFT_00541 | Thi970DRAFT_01977 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.994 |
EIC22902.1 | yajC | Thi970DRAFT_00541 | Thi970DRAFT_03857 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, YajC subunit; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.918 |
EIC22902.1 | yidC | Thi970DRAFT_00541 | Thi970DRAFT_02782 | Protein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Membrane protein insertase, YidC/Oxa1 family, N-terminal domain; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.995 |
EIC24021.1 | EIC19674.1 | Thi970DRAFT_00162 | Thi970DRAFT_03264 | DNA-directed RNA polymerase, beta subunit/140 kD subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb2, domain 6; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb2, domain 7. | Hypothetical protein; Manually curated. | 0.957 |
EIC24021.1 | pheT | Thi970DRAFT_00162 | Thi970DRAFT_04622 | DNA-directed RNA polymerase, beta subunit/140 kD subunit; PFAM: RNA polymerase Rpb1, domain 2; RNA polymerase Rpb2, domain 6; RNA polymerase Rpb1, domain 5; RNA polymerase Rpb2, domain 7. | phenylalanyl-tRNA synthetase, beta subunit; PFAM: tRNA synthetase B5 domain; B3/4 domain; Ferredoxin-fold anticodon binding domain; Putative tRNA binding domain; TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit, non-spirochete bacterial; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.997 |