node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EIC20544.1 | EIC20570.1 | Thi970DRAFT_04187 | Thi970DRAFT_04221 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | 0.798 |
EIC20544.1 | EIC20571.1 | Thi970DRAFT_04187 | Thi970DRAFT_04222 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | 0.720 |
EIC20544.1 | EIC20580.1 | Thi970DRAFT_04187 | Thi970DRAFT_04233 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.528 |
EIC20544.1 | EIC21097.1 | Thi970DRAFT_04187 | Thi970DRAFT_04784 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE. | 0.992 |
EIC20544.1 | EIC21098.1 | Thi970DRAFT_04187 | Thi970DRAFT_04785 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.910 |
EIC20544.1 | EIC21099.1 | Thi970DRAFT_04187 | Thi970DRAFT_04786 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF. | 0.893 |
EIC20544.1 | EIC21913.1 | Thi970DRAFT_04187 | Thi970DRAFT_02149 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF. | 0.502 |
EIC20544.1 | EIC22404.1 | Thi970DRAFT_04187 | Thi970DRAFT_02664 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.866 |
EIC20544.1 | hypA | Thi970DRAFT_04187 | Thi970DRAFT_02619 | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.870 |
EIC20570.1 | EIC20544.1 | Thi970DRAFT_04221 | Thi970DRAFT_04187 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.798 |
EIC20570.1 | EIC20571.1 | Thi970DRAFT_04221 | Thi970DRAFT_04222 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | 0.999 |
EIC20570.1 | EIC20580.1 | Thi970DRAFT_04221 | Thi970DRAFT_04233 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family. | 0.595 |
EIC20570.1 | EIC21097.1 | Thi970DRAFT_04221 | Thi970DRAFT_04784 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | Hydrogenase expression/formation protein HypE; PFAM: AIR synthase related protein, N-terminal domain; AIR synthase related protein, C-terminal domain; TIGRFAM: hydrogenase expression/formation protein HypE. | 0.790 |
EIC20570.1 | EIC21098.1 | Thi970DRAFT_04221 | Thi970DRAFT_04785 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | PFAM: Hydrogenase formation hypA family; TIGRFAM: hydrogenase expression/formation protein HypD; Belongs to the HypD family. | 0.790 |
EIC20570.1 | EIC21099.1 | Thi970DRAFT_04221 | Thi970DRAFT_04786 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | PFAM: HupF/HypC family; TIGRFAM: hydrogenase assembly chaperone HypC/HupF. | 0.741 |
EIC20570.1 | EIC21100.1 | Thi970DRAFT_04221 | Thi970DRAFT_04787 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | Ni,Fe-hydrogenase I large subunit; PFAM: Nickel-dependent hydrogenase. | 0.568 |
EIC20570.1 | EIC22404.1 | Thi970DRAFT_04221 | Thi970DRAFT_02664 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | Hydrogenase accessory protein HypB; PFAM: CobW/HypB/UreG, nucleotide-binding domain; TIGRFAM: hydrogenase accessory protein HypB. | 0.670 |
EIC20570.1 | hypA | Thi970DRAFT_04221 | Thi970DRAFT_02619 | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | Zn finger protein HypA/HybF (possibly regulating hydrogenase expression); Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. | 0.620 |
EIC20571.1 | EIC20544.1 | Thi970DRAFT_04222 | Thi970DRAFT_04187 | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | (NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. | 0.720 |
EIC20571.1 | EIC20570.1 | Thi970DRAFT_04222 | Thi970DRAFT_04221 | Coenzyme F420-reducing hydrogenase, gamma subunit; PFAM: NADH ubiquinone oxidoreductase, 20 Kd subunit. | Coenzyme F420-reducing hydrogenase, alpha subunit; PFAM: Nickel-dependent hydrogenase. | 0.999 |