N177_1653 protein (Lutibaculum baratangense)

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second shell of interactors

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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gene co-occurrence

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co-expression

protein homology

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Score

N177_1653

ABC transporter, periplasmic substrate-binding protein. (617 aa)

Predicted Functional Partners:

N177_1656

0.972

N177_1655

0.959

N177_1658

0.956

N177_1654

0.955

N177_2239

0.865

N177_1657

0.741

N177_2241

0.661

N177_1659

0.648

N177_3002

0.531

N177_2137

0.513

Your Current Organism:

Lutibaculum baratangense

NCBI taxonomy Id: 631454
Other names: L. baratangense AMV1, Lutibaculum baratangense AMV1, Phyllobacteriaceae bacterium AMV1

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Browse interactions in tabular form:

node1	node2	node1 annotation	node2 annotation	score
N177_1653	N177_1654	ABC transporter, periplasmic substrate-binding protein.	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	0.955
N177_1653	N177_1655	ABC transporter, periplasmic substrate-binding protein.	Oligopeptide transport system permease protein OppB; TCDB 3.A.1.5.1.	0.959
N177_1653	N177_1656	ABC transporter, periplasmic substrate-binding protein.	Oligopeptide transport system permease protein OppC; TCDB 3.A.1.5.1.	0.972
N177_1653	N177_1657	ABC transporter, periplasmic substrate-binding protein.	Cobalt-zinc-cadmium resistance protein CzcD.	0.741
N177_1653	N177_1658	ABC transporter, periplasmic substrate-binding protein.	Oligopeptide transport system permease protein OppB; TCDB 3.A.1.5.1; Belongs to the ABC transporter superfamily.	0.956
N177_1653	N177_1659	ABC transporter, periplasmic substrate-binding protein.	D-3-phosphoglycerate dehydrogenase.	0.648
N177_1653	N177_2137	ABC transporter, periplasmic substrate-binding protein.	Oligopeptide transport ATP-binding protein OppD; TCDB 3.A.1.5.1; Belongs to the ABC transporter superfamily.	0.513
N177_1653	N177_2239	ABC transporter, periplasmic substrate-binding protein.	Putative oligopeptide ABC transporter, permease component.	0.865
N177_1653	N177_2241	ABC transporter, periplasmic substrate-binding protein.	Putative ATP-binding component of ABC transporter.	0.661
N177_1653	N177_3002	ABC transporter, periplasmic substrate-binding protein.	Oligopeptide transport ATP-binding protein OppF; TCDB 3.A.1.5.1; Belongs to the ABC transporter superfamily.	0.531
N177_1654	N177_1653	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	ABC transporter, periplasmic substrate-binding protein.	0.955
N177_1654	N177_1655	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Oligopeptide transport system permease protein OppB; TCDB 3.A.1.5.1.	0.964
N177_1654	N177_1656	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Oligopeptide transport system permease protein OppC; TCDB 3.A.1.5.1.	0.975
N177_1654	N177_1657	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Cobalt-zinc-cadmium resistance protein CzcD.	0.741
N177_1654	N177_1658	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Oligopeptide transport system permease protein OppB; TCDB 3.A.1.5.1; Belongs to the ABC transporter superfamily.	0.958
N177_1654	N177_1659	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	D-3-phosphoglycerate dehydrogenase.	0.648
N177_1654	N177_2137	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Oligopeptide transport ATP-binding protein OppD; TCDB 3.A.1.5.1; Belongs to the ABC transporter superfamily.	0.522
N177_1654	N177_2239	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Putative oligopeptide ABC transporter, permease component.	0.865
N177_1654	N177_2241	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Putative ATP-binding component of ABC transporter.	0.667
N177_1654	N177_3002	Oligopeptide ABC transporter, periplasmic oligopeptide-binding protein OppA; TCDB 3.A.1.5.1.	Oligopeptide transport ATP-binding protein OppF; TCDB 3.A.1.5.1; Belongs to the ABC transporter superfamily.	0.531

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Network Stats

number of nodes:

11

number of edges:

39

average node degree:

7.09

avg. local clustering coefficient:

0.95

expected number of edges:

25

PPI enrichment p-value:

0.00477

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

7 of 98

1.44

1.91

1.55e-06

GO:0010467

Gene expression

8 of 203

1.18

1.43

1.55e-06

GO:0009059

Macromolecule biosynthetic process

8 of 233

1.12

1.3

2.53e-06

GO:0044271

Cellular nitrogen compound biosynthetic process

8 of 314

0.99

1.02

1.67e-05

GO:0009987

Cellular process

10 of 1616

0.37

0.27

0.0284

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

6 of 54

1.63

2.24

1.49e-06

GO:0019843

rRNA binding

4 of 40

1.58

1.42

0.00057

GO:0000049

tRNA binding

3 of 20

1.76

1.3

0.0020

GO:0003723

RNA binding

5 of 98

1.29

1.17

0.00057

GO:0005525

GTP binding

3 of 32

1.55

1.02

0.0062

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

6 of 62

1.57

2.23

6.25e-07

GO:0044391

Ribosomal subunit

3 of 13

1.94

1.91

0.00012

GO:0015935

Small ribosomal subunit

2 of 6

2.1

1.39

0.0022

GO:0032991

Protein-containing complex

4 of 119

1.11

0.88

0.0022

GO:0005622

Intracellular anatomical structure

8 of 885

0.54

0.41

0.0036

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:300

Ribosome

8 of 61

1.7

3.23

4.70e-10

CL:304

Ribosome

7 of 52

1.71

3.07

3.34e-09

CL:306

rRNA-binding

4 of 27

1.75

1.93

4.70e-05

CL:366

Ribosome

3 of 13

1.94

1.67

0.00042

CL:368

Structural constituent of ribosome

2 of 6

2.1

1.1

0.0082

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

sgn03010

Ribosome

6 of 55

1.62

2.4

3.23e-07

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009507

Chloroplast

3 of 25

1.66

0.98

0.0100

GOCC:0005840

Ribosome

3 of 39

1.47

0.91

0.0100

GOCC:0043229

Intracellular organelle

6 of 288

0.9

0.61

0.0100

GOCC:0005622

Intracellular

9 of 959

0.55

0.39

0.0100

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

6 of 58

1.6

2.26

7.88e-07

KW-0699

rRNA-binding

3 of 37

1.49

0.96

0.0077

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF03144

Elongation factor Tu domain 2

2 of 4

2.28

0.78

0.0376

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR005225

Small GTP-binding protein domain

3 of 10

2.06

1.25

0.0041

IPR035647

EF-G domain III/V-like

2 of 4

2.28

0.8

0.0340

IPR031157

Tr-type G domain, conserved site

2 of 4

2.28

0.8

0.0340

IPR004161

Translation elongation factor EFTu-like, domain 2

2 of 4

2.28

0.8

0.0340

IPR000640

Elongation factor EFG, domain V-like

2 of 3

2.41

0.8

0.0340

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00838

Elongation factor G C-terminus

2 of 3

2.41

1.2

0.0061

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