node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
N177_0361 | N177_0363 | N177_0361 | N177_0363 | Para-aminobenzoate synthase, aminase component. | Aminodeoxychorismate lyase. | 0.981 |
N177_0361 | N177_2634 | N177_0361 | N177_2634 | Para-aminobenzoate synthase, aminase component. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.776 |
N177_0361 | N177_2635 | N177_0361 | N177_2635 | Para-aminobenzoate synthase, aminase component. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.447 |
N177_0361 | N177_2636 | N177_0361 | N177_2636 | Para-aminobenzoate synthase, aminase component. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.814 |
N177_0361 | trpE | N177_0361 | N177_3559 | Para-aminobenzoate synthase, aminase component. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.650 |
N177_0363 | N177_0361 | N177_0363 | N177_0361 | Aminodeoxychorismate lyase. | Para-aminobenzoate synthase, aminase component. | 0.981 |
N177_0363 | N177_2634 | N177_0363 | N177_2634 | Aminodeoxychorismate lyase. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.485 |
N177_0363 | N177_2636 | N177_0363 | N177_2636 | Aminodeoxychorismate lyase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.825 |
N177_0363 | trpE | N177_0363 | N177_3559 | Aminodeoxychorismate lyase. | Anthranilate synthase, aminase component; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high c [...] | 0.731 |
N177_1261 | N177_2634 | N177_1261 | N177_2634 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | 0.961 |
N177_1261 | N177_2635 | N177_1261 | N177_2635 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.840 |
N177_1261 | N177_2636 | N177_1261 | N177_2636 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
N177_1261 | folE | N177_1261 | N177_4161 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | GTP cyclohydrolase I type 1. | 0.638 |
N177_1261 | glyA | N177_1261 | N177_3333 | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.719 |
N177_2634 | N177_0361 | N177_2634 | N177_0361 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Para-aminobenzoate synthase, aminase component. | 0.776 |
N177_2634 | N177_0363 | N177_2634 | N177_0363 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Aminodeoxychorismate lyase. | 0.485 |
N177_2634 | N177_1261 | N177_2634 | N177_1261 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. | 0.961 |
N177_2634 | N177_2635 | N177_2634 | N177_2635 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.999 |
N177_2634 | N177_2636 | N177_2634 | N177_2636 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.999 |
N177_2634 | folE | N177_2634 | N177_4161 | 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. | GTP cyclohydrolase I type 1. | 0.999 |