STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
N177_3863Acetolactate synthase small subunit. (171 aa)    
Predicted Functional Partners:
N177_3865
Acetolactate synthase large subunit.
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.998
N177_0648
Acetolactate synthase large subunit; Belongs to the TPP enzyme family.
 0.982
N177_1164
Thiamine pyrophosphate-requiring enzyme; Belongs to the TPP enzyme family.
 
 0.979
N177_0504
Oxalyl-CoA decarboxylase; Belongs to the TPP enzyme family.
  
 0.960
N177_1583
Acetohydroxy acid synthase; Belongs to the TPP enzyme family.
 
 0.957
N177_2685
Threonine dehydratase, catabolic.
  
 
 0.953
N177_3378
Homoserine dehydrogenase.
  
 
 0.951
N177_0379
TPP-requiring enzyme co-localized with fatty acid metabolic; Belongs to the TPP enzyme family.
 
 0.945
N177_1861
Thiamine pyrophosphate-requiring enzyme; Belongs to the TPP enzyme family.
 
 0.945
Your Current Organism:
Lutibaculum baratangense
NCBI taxonomy Id: 631454
Other names: L. baratangense AMV1, Lutibaculum baratangense AMV1, Phyllobacteriaceae bacterium AMV1
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