STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95093.1Conserved protein distantly related to 6-phosphogluconolactonases; Localized in the cytoplasm; Function unclear. (355 aa)    
Predicted Functional Partners:
CAZ97731.1
3-carboxymuconate cyclase-like protein; Possible 3-carboxymuconate cyclase, which converts by isomerisation the 3-carboxy-2,5-dihydro-5-oxofuran-2-acetate to 3-carboxy-cis,cis-muconate; Contains a signal peptide of lipoprotein cleaved between the residues 19 and 20; Belongs to the cycloisomerase 2 family; Localized in the cytoplasmic membrane; Family membership.
  
  
 
0.925
zwfA
Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
    
 0.916
gndA
6-Phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
    
 0.916
pglA
6-Phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
     
 0.901
gntK1
Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity.
     
 0.900
gntK2
Gluconokinase is involved in the gluconate catabolism pathway (Pentose phosphate pathway). It converts the D-gluconate to 6-phospho-D-gluconate; GntK adopts an alpha/beta fold, consisting of a central sheet of five parallel beta-strands flanked by alpha-helices; Belongs to the shikimate kinase family; Localized in the cytoplasm; High confidence in function and specificity.
     
 0.900
CAZ95096.1
Dioxygenase, PhyH family; Dioxygenase catalyzes the incorporation of both atoms of oxygen from one molecule of O2 into the (reduced) substrate. The exact specificity of this enzyme is unknown; Belongs to the phytanoyl-CoA dioxygenase (PhyH) family; Localized in the cytoplasm; Family membership.
       0.499
CAZ95095.1
Oxydoreductase NADPH dependent; Belongs to the aldo/keto reductase 2 family; localized in the cytoplasm; Family membership.
  
    0.497
CAZ95094.1
Conserved protein belonging to the creatinase family, but its exact function is unclear; Localized in the cytoplasm; Family membership.
       0.490
CAZ95097.1
Sodium/solute symporter; Modular protein containing a N-terminal 7-bladed beta propeller domain (Galactose oxidase central domain family) and a C-terminal Sodium-solute symporter. Sodium/substrate symport is a widespread mechanism of solute transport across cytoplasmic membranes of cells. Thereby the energy stored in an inwardly directed electrochemical sodium gradient (sodium motive force, SMF) is used to drive solute accumulation against a concentration gradient; Contains thirteen transmembrane helices; Localized in the cytoplasmic membrane; Specificity unclear.
       0.466
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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