STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95102.1Conserved hypothetical protein; Localized in the cytoplasm. (380 aa)    
Predicted Functional Partners:
frcA
Formyl-coenzyme A transferase catalyzes the first step of the oxalic acid catabolism. It transfers the CoA moiety from formyl-CoA to oxalate. FcrA belongs to the CoA-transferase family III and forms a homodimer. Localized in the cytoplasm; High confidence in function and specificity.
 
     0.930
CAZ95817.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes of the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership.
  
 
 0.888
paaF
The enoyl-CoA hydratase (ECH) is an enzyme involved in fatty acid metabolism. It catalyzes the hydratation of 2-trans-enoyl-CoA into 3-hydroxyacyl-CoA; High confidence in function and specificity.
  
  
 0.794
CAZ95101.1
N-acetyl-D-glucosamine 2-epimerase catalyzes the interconversion of N-acetylglucosamine to N-acetylmannosamine. It functions as a homodimer, where monomer has an alpha(6)/alpha(6)-barrel structure commonly found in glucoamylases and cellulases This enzyme is involved in sialic acid metabolism. Localized in the cytoplasm; High confidence in function and specificity.
     
 0.603
fabG3
3-Oxoacyl-[acyl-carrier-protein] reductase; Involved in first reduction step of the fatty acid biosynthesis pathway. Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily. Contains a signal peptide cleaved between the residues 27 and 28. Localized in the periplasmic space; High confidence in function and specificity.
  
    0.581
CAZ98793.1
Galactonate dehydratase is involved in the galactose metabolism. It converts the D-galactonate to 2-dehydro-3-deoxy-D-galactonate; Contains a N-terminal domain with a Enolase N-terminal domain-like fold and a C-terminal TIM alpha/beta barrel fold; Belongs to the Mandelate racemase / muconate lactonizing enzyme family; Localized in the cytoplasm; High confidence in function and specificity.
 
     0.438
rraA1
Regulator of ribonuclease activity is a general modulator of RNA abundance which inhibits the endonuclease activity of the RNase E and thereby leads to increase the half-life of RNAs; Contains a Demethylmenaquinone methyltransferase domain; Localized in the cytoplasm; Conserved hypothetical protein.
 
     0.433
CAZ96463.1
Conserved hypothetical protein; Shows a weak similarity with the glycoside hydrolases of the family 42 (GH42); Seems to be a lipoprotein with a signal peptide cleaved between residues 15 and 16; Putatively localised in the outer membrane.
 
  
 0.423
nanA3
N-acetylneuraminate lyase is involved in sialic acid metabolism. It catalyzes the cleavage of N-acetylneuraminic acid (sialic acid) to form pyruvate and N-acetylmannosamine via a Schiff base intermediate. NanA belongs to the dihidropicolinate synthase (DHDPS) family and forms a homotetramer. Localized in the cytoplasm; High confidence in function and specificity.
       0.411
rraA2
Dimethylmenaquinone methyltransferase; Regulator of ribonuclease activity is a general modulator of RNA abundance which inhibits the endonuclease activity of the RNase E and thereby leads to increase the half-life of RNAs; Contains a Demethylmenaquinone methyltransferase domain; Localized in the cytoplasm; Conserved hypothetical protein.
 
     0.400
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.