STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cspA1Cold shock proteins (CSPs) help the cell to survive in temperatures lower than optimum growth temperature. CSPs may act as RNA chaperones by destabilizing RNA secondary structures, regulating ribosomal translation, rate of mRNA degradation and termination of transcription; Contains a 'cold-shock domain' (CSD) involved in the single-strand nucleic-acid binding; Localized in the cytoplasm; High confidence in function and specificity. (63 aa)    
Predicted Functional Partners:
CAZ95123.1
DEAD/DEAH RNA helicase; Protein that could be involved in ATP-dependent RNA unwinding in a variety of cellular processes, including ribosome assembly, protein synthesis, and RNA degradation; Contains a DEAD box; Belongs to the helicases superfamily II, DEAD/DEAH box RNA helicase family, DEAD box subfamily; Localized in the cytoplasm; Family membership.
  
 
 0.785
des6-2
Linoleoyl-CoA desaturase, also known as delta 6-desaturase, is responsible for the conversion of linoleic acid (18:2) to gamma-linolenic acid (18:3 gamma). It uses iron ion as a cofactor. Features five transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
     
 0.703
CAZ98902.1
Conserved hypothetical protein. Localized in the cytoplasm.
   
 
 0.527
rpoB
DNA-dependent RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.524
rpoA
DNA-dependent RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.505
rpmE
Protein L31 is a part of the large subunit (50S) of the ribosome; Belongs to the ribosomal protein L31p family, type B subfamily; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.467
rpsL
Ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
   
 
 0.454
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
   
 
 0.418
rpsB
The ribosomal protein S2 is a part of the ribosomal small subunit (30S) that contributes to the structural integrity of the ribosome; Belongs to the ribosomal protein S2p family; Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.412
rpsE
Ribosomal protein S5; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family.
   
 
 0.409
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.