STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95129.1Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership. (247 aa)    
Predicted Functional Partners:
CAZ95130.1
Conserved hypothetical protein; Localized in the cytoplasm.
       0.615
hdhA
7-Alpha-hydroxysteroid dehydrogenase; HdhA catalyzes the 7-alpha-dehydroxylation of cholic acid, yielding deoxycholic acid and lithocholic acid, respectively. Highest affinity with taurochenodeoxycholic acid. It forms a homotetramer and binds one NAD cofactor by subunit. Belongs to the short chain dehydrogenase family. Localized in the cytoplasm; Hypothetical protein.
   
0.552
CAZ95131.1
Conserved hypothetical protein belonging to the DUF20 family proteins. This family is predicted to be composed of permeases; Contains eight transmembrane helices; Localized in the cytoplasmic membrane; Family membership.
       0.527
CAZ95128.1
Conserved protein distantly related to the ribonuclease BN, a 3' to 5' exoribonuclease necessary for 3' maturation of tRNA molecules; Contains six transmembrane helices; Localized in the cytoplasmic membrane; Family membership.
       0.508
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
 
  
 0.496
CAZ98109.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership.
 
    0.453
CAZ98521.1
Belongs to the short-chain dehydrogenases/reductases (SDR) family, Glucose/ribitol dehydrogenase subfamily; Most dehydrogenases possess at least 2 domains, the first binding the coenzyme, often NAD, and the second binding the substrate. This latter domain determines the substrate specificity and contains amino acids involved in catalysis; Localized in the cytoplasm; Family membership.
 
    0.453
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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