STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
gdhAGlucose dehydrogenase catalyses the oxidation of D-glucose without prior phosphorylation to D-beta-gluconolactone using NAD or NADP as a coenzyme; Belongs to the short-chain dehydrogenases/reductases family, Glucose/ribitol dehydrogenase subfamily; Localized in the cytoplasm; High confidence in function and specificity. (272 aa)    
Predicted Functional Partners:
gnlA
Gluconolactonases hydrolyze the gluconolactone, formed either by the glucose oxidoreductase or by the glucose dehydrogenase in aerobic conditions, to gluconate; Contains a putative lipoprotein signal peptide cleaved between the residues 20 and 21; Possibly localized in the outer membrane; High confidence in function and specificity.
  
 
 0.902
CAZ94658.1
Gluconolactonases hydrolyze the gluconolactone formed by glucose oxidoreductase. The proximity of the galactonate dehydratase gene dgoD suggests that this lactonase would be specific for D-galactono-1,4-lactone instead of gluconolactone; Signal peptide cleaved between the residues 19 and 20; Localized in the periplasm; Specificity unclear.
  
 
 0.902
gapD
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity.
   
 0.836
gapA
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity.
   
 0.832
gapB
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3-phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity.
   
 0.832
gapC
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) catalyzes the sixth step of glycolysis (Embden-Meyerhof pathway) and thus serves to break down glucose for energy and carbon molecules by reversibly catalysing the oxidation and phosphorylation of D-glyceraldehyde-3- phosphate to 1,3-diphospho-glycerate. Also it plays an important role in gluconeogenesis; Acts as an homotetramer; Localized in the cytoplasm; High confidence in function and specificity.
   
 0.832
gapN
The NADP-dependent glyceraldehyde-3-phosphate dehydrogenase is important as a means of generating NADPH for biosynthetic reactions. It converts the D-glyceraldehyde 3-phosphate to 3-phospho-D-glycerate; Forms a homotetramer and binds a NADP+ per subunit as cofactors; Localized in the cytoplasm; High confidence in function and specificity.
  
  0.822
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
   
 0.821
enoA
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
   
 0.817
pgcA
Phosphoglucomutase catalyzes the interconversion between glucose-6-phosphate and alpha-glucose-1-phosphate. It participates in both the breakdown and synthesis of glucose. Binds one magnesium as cofactor. Localized in the cytoplasm; High confidence in function and specificity.
   
 0.817
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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