STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95221.1Metal transport-related protein; Seems to contain a Heavy metal associated domain (HMA domain) being involved in bacterial resistance to toxic metals; Signal peptide cleaved between the residues 19 and 20; Exported in the periplasmic space; Conserved hypothetical protein. (118 aa)    
Predicted Functional Partners:
CAZ95222.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Contains a carboxypeptidase regulatory domain (21-98) and the Plug module (115-222) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership.
     0.986
actP
ActP is a P-type ATPase responsible for copper efflux using ATP hydrolysis for energy. ActP controls copper homeostasis. Belongs to the cation transport P-type ATPase family. Features eight transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 
 0.861
sodC
Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.
   
 0.756
CAZ95745.1
Conserved hypothetical lipoprotein; Contains a prokaryotic lipoprotein signal peptide cleaved between the residues 19 and 20; Localized in the outer membrane; Conserved hypothetical protein.
   
 0.756
ziaA
ZiaA is a P-type ATPase responsible for zinc efflux using ATP hydrolysis for energy. ZiaA controls zinc homeostasis. Belongs to the cation transport P-type ATPase family. Features six transmembrane helices. Localized in the cytoplasmic membrane; High confidence in function and specificity.
  
 
 0.609
ccoI
Belongs to the cation transport P-type ATPase family. Involved in the ccoGHIS operon. Features eight transmembrane helices. Localized in the cytoplasmic membrane; Hypothetical protein.
  
 
 0.603
CAZ96425.1
Transcriptional repressor. The BlaI like repressors form homodimers that specifically bind DNA operator/promoter sequences. Followed by a blaR1-like regulator protein; High confidence in function and specificity.
  
  
 0.537
CAZ96442.1
BlaI-type transcriptional regulator are repressors usually involved in regulation of resistance to beta-lactams; The N-terminal region of these proteins is involved in DNA operator sequence recognition, while the C-terminal is responsible for dimerisation of the protein; Localized in the cytoplasm; High confidence in function and specificity.
  
  
 0.537
CAZ95224.1
The AraC-type transcriptional regulators are usually involved in the positive regulation of catabolic, metabolic and transport operons; Contains a C-terminal AraC-type HTH DNA-binding domain involved in the binding of the protein to the operator sequences in the DNA. Also would contain an N-terminal heavy-metal-associated domain (HMA) involved in the transport or detoxification of heavy metals; Localized in the cytoplasm; Family membership.
       0.494
CAZ98871.1
Conserved beta helix fold protein; Possible lipoprotein that consists of a pectin lyase like domain suggesting a beta helix fold for this protein; Signal peptide cleaved between the residues 25 and 26; probably localized in the outer membrane; Conserved hypothetical protein.
  
     0.470
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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