STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95310.1Conserved hypothetical membrane protein; Contains a central transmembrane helix; Localized in the cytoplasmic membrane; Conserved hypothetical protein. (383 aa)    
Predicted Functional Partners:
CAZ97540.1
Conserved hypothetical protein; Localized in the cytoplasm.
   
 0.710
CAZ98039.1
The sensor histidine kinase belongs to two-component signal transduction systems. It autophosphorylates an histidine in its phosphoacceptor domain and phosphorylates an aspartic acid present in the response regulator receiver domain; Contains a CheB-type methylesterase catalytic domain and a CheR-type methyltransferase domain, both involved in the bacterial chemotaxis system; Contains a PAS/PAC domain; Seems localized in the cytoplasm; Family membership.
   
 
 0.565
CAZ97982.1
The sensor histidine kinase belongs to two-component signal transduction systems. It autophosphorylates a conserved histidine in its phosphoacceptor domain and phosphorylates the receiver domain of response regulator; Contains three N-terminal PAS/PAC domains and a GAF domain is present in the central part of the protein. The Histidine kinase domain is localized in the C-terminal end; Seems localized in the cytoplasm; Family membership.
  
 
 0.533
bgaD
Beta-galactosidase, family GH2; Enzyme belonging to the family 2 of glycoside hydrolases (GH2) which catalyzes the hydrolysis of the beta-1,4 linkage at the terminal non-reducing of beta-D-galactosides, releasing a beta-D-galactose residue; Signal peptide cleaved between residues 22 and 23; Localized in the periplasmic space; High confidence in function and specificity.
       0.485
CAZ97983.1
Cyclic nucleotide-binding dependent two-component system-Response regulator; The response regulators are involved in the two-component signal transduction systems to detect and respond to environmental changes. These proteins consist of a N-terminal receiver domain that is substrate for a histidine protein kinase sensor, a cyclic nucleotide-binding domain and a C-terminal Crp-type HTH domain (effector domain); The Crp-type HTH domain binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons; Specificity unclear.
  
 0.472
CAZ94252.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains a transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
  
 
 0.458
CAZ96376.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
  
 
 0.458
CAZ96458.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
  
 
 0.458
CAZ94342.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains two transmembrane segments; Localized in the cytoplasmic membrane; Family membership.
  
 
 0.458
CAZ94421.1
The sensor proteins consist of a sensing beta-propeller fold periplasmic domain, variable in sequence, reflective of the many different environmental signals, and of a cytoplasmic part composed of a histidine kinase domain, a response regulator receiver domain and a response regulator effector domain (here a C-terminal AraC- type HTH domain); Contains one transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
  
 
 0.458
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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