STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95341.1ABC-1 type exporter, ATP-binding/permease protein; The ABC-1 type transporters have their ABC membrane domain and their ABC ATPase domain fused in the same protein. They are involved in the efflux of compounds across the biological membranes or in targeting of membrane components; Contains six N-terminal transmembrane segments (ABC membrane) that form a pore in the cytoplasmic membrane an a C-terminal ATP-binding domain (ABC ATPase) responsible for energy generation; Belongs to the ABC-1 type transporter permease/ATP-binding family, lipid exporter subfamily (msbA subfamily); Family mem [...] (578 aa)    
Predicted Functional Partners:
CAZ95817.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes of the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership.
 
 
  
0.731
CAZ94457.1
Type I polyketide synthases are modular enzymes involved in the synthesis of various polyketides. This enzyme encompasses five modules: beta-ketoacyl synthase (KS), acyltransferase (AC), dehydratase (DH), enoyl reductase (ER) and acyl carrier protein (ACP). This modular enzyme is homologous to mycocerosic acid synthase (EC 2.3.1.111). Binds 1 phosphopantetheine group covalently. Localized in the cytoplasmic membrane; Specificity unclear.
 
 0.581
CAZ95340.1
Conserved protein belonging to the DUF477 family; Contains three transmembrane helices in the C-terminal region; Signal peptide cleaved between the residues 19 and 20; Localized in the cytoplasmic membrane; Family membership.
       0.534
CAZ95339.1
Glutaryl-7-aminocephalosporanic-acid acylase, also known as cephalosporin acylase (CA), hydrolyzes the (7R)-7-(4-carboxybutanamido)cephalosporanate to (7R)-7-aminocephalosporanate and glutarate. The form catalytically active of CA, an alpha-beta dimer, is obtained by two proteolytic cleavages; Belongs to the family S45 of the serine peptidases; Contains an uncleavable signal peptide; Localized into the cytoplasmic membrane; High confidence in function and specificity.
 
     0.527
CAZ95577.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase) encoded by a different gene of those that encode for the ABC transporter permease component (ABC membrane); Family membership.
 
   
0.503
acpP4
Acyl carrier protein (ACP) is the carrier of the growing fatty acid chain in fatty acid biosynthesis. ACP is produced as an apoprotein and is converted to its active form by [ACP]synthase (AcpS); Localized in the cytoplasm; High confidence in function and specificity.
  
 
 0.404
dnaK
Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.400
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
Server load: low (20%) [HD]