STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ftsXCell division protein FtsX; Required for cell division and gliding motility. Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (292 aa)    
Predicted Functional Partners:
CAZ96883.1
ABC transporter, ATPase component; This protein is the nucleotide-binding domain of the ABC transporters (ABC ATPase); Responsible for coupling the energy of ATP hydrolysis to conformational changes in the permease component (ABC membrane); Localized in the cytoplasmic membrane as a peripheral membrane protein; Family membership.
 
 
 0.976
CAZ95841.1
Family M23 non-peptidase protein; This protein displays significant similarity with the metallopeptidases from the family M23, but the ligands of the catalytic zinc are missing (motifs HXXXD and HXH). Peptidase family M23 mainly contains endopeptidases that lyze bacterial cell wall peptidoglycans; Contains a signal peptide cleaved between the residues 26 and 27; Localized in the periplasm; Function unclear.
 
 
 
 0.926
CAZ95377.1
Conserved hypothetical membrane protein; Contains two transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
     0.713
uppP
Undecaprenyl-diphosphatase; Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin; Belongs to the UppP family.
  
    0.651
mltG
Conserved hypothetical periplasmic protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.
 
  
 0.589
leuS
Leucyl-tRNA synthetase catalyses the attachment of leucine to its cognate transfer RNA molecule in a highly specific two-step reaction. Belongs to the class I of the aminoacyl-tRNA synthetases. It is a monomer and adopts a Rossmann fold. Localized in the cytoplasm; High confidence in function and specificity.
       0.586
truB
tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.
       0.575
mraZ
Protein that could play a role in cell-wall biosynthesis and/or cell division. However, to date, there has been no clear functional assignment provided for MraZ protein. MraZ is a homooctamer or homododecamer to forms a ring; Localized in the cytoplasm; Function unclear.
  
   
 0.514
CAZ95374.1
Conserved hypothetical membrane protein; Contains three transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
       0.497
amiA
N-acetylmuramoyl-L-alanine amidase; The protein contains two domains. A N-terminal N-acetylmuramoyl-L-alanine amidase domain (230 residues) that hydrolyzes the amide bond between N-acetylmuramoyl residues and L-amino acid residues in bacterial cell walls and a C-terminal domain (200 residues) of unknown function; Contains one N-terminal transmembrane segment; Belongs to the N-acetylmuramoyl-L-alanine amidase 3 family; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
   
 0.446
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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