STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ95396.1TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Does not contain of carboxypeptidase regulatory domain; Contains the Plug module (44-155) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership. (710 aa)    
Predicted Functional Partners:
pnuC1
PnuC is a membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
  
 0.666
CAZ97875.1
Conserved hypothetical protein. Localized in the cytoplasm.
 
     0.574
tolA
TolA, involved in the tonB-independent uptake of proteins, interacts with the TolQ and TolR, cytoplasmic membrane proteins and with the Pal protein (OprL) in the outer membrane. The transport is energized by the proton motive force. The Tol-Pal complex is required for maintaining outer membrane integrity, the transport (uptake) filamentous DNA and is the conduct for bacteriophages; TolA is anchored to the cytoplasmic membrane by a single transmembrane spanning segment near the N-terminus, leaving most of the protein exposed to the periplasm; High confidence in function and specificity.
 
   0.567
CAZ96927.1
Conserved hypothetical membrane protein; Contains five transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
  
     0.541
sprA-2
Conserved hypothetical periplasmic protein; Signal peptide cleaved between the resedues 31 and 32; Localized in the periplasmic space; Conserved hypothetical protein.
  
     0.511
CAZ95397.1
Putative protein.
       0.501
CAZ95395.1
NAD(P)-dependent oxidoreductase belonging to the GFO/IDH/MOCA family. Adopts a Rossmann fold; Localized in the cytoplasm; Specificity unclear.
       0.499
tonB2
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   0.483
tonB1
TonB protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
   0.482
CAZ96800.1
TonB-like protein; TonB is an energy-transducer for TonB-dependent receptors of Gram-negative bacteria. Energy flows from the cytoplasmic membrane into the outer membrane via a complex consisting of TonB, ExbB and ExbD proteins which are anchored in the cytoplasmic membrane. TonB interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates; Although belonging to the TonB family, this protein seems to contain a signal peptide cleaved between the residues 17 and 18, which is unsual for c [...]
 
   0.468
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.