STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CAZ95405.1Conserved hypothetical protein; Protein that displays similarity with the C-terminal region of the transcriptional regulator nadR; Localized in the cytoplasm. (157 aa)    
Predicted Functional Partners:
CAZ95404.1
Conserved hypothetical protein; Localized in the cytoplasm.
      0.978
pnuC1
PnuC is a membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
   
 0.905
CAZ95407.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.850
nadR
Nicotinamide-nucleotide adenylyltransferase / Ribosylnicotinamide kinase; Bifunctional enzyme involved in the nicotinate and nicotinamide metabolism possessing both NMN (nicotinamide mononucleotide) adenylytransferase (NMNAT) and Ribosylnicotinamide kinase (RNK) activities. NMNAT is an indispensable activity in the biosynthesis of NAD(+) and NADP(+) synthesizing NAD via the salvage pathway. RNK converts the N-ribosylnicotinamide to nicotinamide ribonucleotide; Localized in the cytoplasm. However, this bifunctional enzyme would loosely associate with the membrane through its interaction [...]
 
     0.685
CAZ95408.1
Conserved protein belonging to the 4'-phosphopantetheinyl transferase family; The members of this family activates enzymes and carrier proteins, by transferring the phophopantethiene prosthetic group of coenzyme A to its attachment site (a serine residue). Many members of the family are small proteins that act on the acyl carrier protein involved in fatty acid biosynthesis; Uses magnesium ion as cofactor; Localized in the cytoplasm; Family membership.
 
     0.617
pnuC2
PnuC is the membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity.
 
   
 0.583
nadC
Quinolinic acid phosphoribosyl transferase (QPRTase or QAPRTase) or nicotinate-nucleotide pyrophosphorylase catalyses the conversion of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP), in the presence of Mg2+, to nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide. This enzyme provides the de novo source of NAMN for NAD biosynthesis; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the NadC/ModD family.
     
 0.555
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
     
 0.555
npdA
NAD-dependent deacetylase activates the enzyme acetyl-CoA synthetase by deacetylating its catalytic Lysine in the inactive, acetylated form of the enzyme. May also modulate the activity of other propionyl-adenosine monophosphate (AMP)-forming enzymes. It binds one zinc ion as a cofactor. Localized in the cytoplasm; High confidence in function and specificity; Belongs to the sirtuin family. Class III subfamily.
   
    0.505
CAZ95403.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 19 and 20; Localized in the periplasmic space; Conserved hypothetical protein.
       0.429
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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