STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pnuC1PnuC is a membrane protein responsible for nicotinamide mononucleotide transport; Contains seven transmembrane helices; Localized in the cytoplasmic membrane; High confidence in function and specificity. (212 aa)    
Predicted Functional Partners:
CAZ95407.1
Conserved hypothetical protein; Localized in the cytoplasm.
 
     0.907
CAZ95405.1
Conserved hypothetical protein; Protein that displays similarity with the C-terminal region of the transcriptional regulator nadR; Localized in the cytoplasm.
 
   
 0.905
nadR
Nicotinamide-nucleotide adenylyltransferase / Ribosylnicotinamide kinase; Bifunctional enzyme involved in the nicotinate and nicotinamide metabolism possessing both NMN (nicotinamide mononucleotide) adenylytransferase (NMNAT) and Ribosylnicotinamide kinase (RNK) activities. NMNAT is an indispensable activity in the biosynthesis of NAD(+) and NADP(+) synthesizing NAD via the salvage pathway. RNK converts the N-ribosylnicotinamide to nicotinamide ribonucleotide; Localized in the cytoplasm. However, this bifunctional enzyme would loosely associate with the membrane through its interaction [...]
 
   
 0.734
CAZ95404.1
Conserved hypothetical protein; Localized in the cytoplasm.
     
 0.729
CAZ95408.1
Conserved protein belonging to the 4'-phosphopantetheinyl transferase family; The members of this family activates enzymes and carrier proteins, by transferring the phophopantethiene prosthetic group of coenzyme A to its attachment site (a serine residue). Many members of the family are small proteins that act on the acyl carrier protein involved in fatty acid biosynthesis; Uses magnesium ion as cofactor; Localized in the cytoplasm; Family membership.
 
     0.684
CAZ95396.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Does not contain of carboxypeptidase regulatory domain; Contains the Plug module (44-155) acting as a channel gate; The signal peptide is cleaved between the residues 19 and 20; Family membership.
 
  
 0.666
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
       0.451
CAZ95576.1
Conserved hypothetical protein; Protein Localized in the cytoplasm.
 
     0.425
CAZ97390.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations; Does not contain of carboxypeptidase regulatory domain. The Plug module (41-152) acts as a channel gate; The signal peptide is cleaved between the residues 20 and 21; Family membership.
 
  
 0.419
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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