STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pcdAPiperideine-6-carboxylate dehydrogenase, aldehyde dehydrogenase family; Piperideine-6-carboxylate dehydrogenase catalyses the conversion of Delta-1-Piperideine-6-carboxylate into alpha-aminoadipic acid. This latter compound is a precursor of cephamycin C antibiotic; Localized in the cytoplasm; High confidence in function and specificity. (517 aa)    
Predicted Functional Partners:
acs
Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA.
  
 0.943
CAZ95622.1
Aminotransferases share certain mechanistic features with other pyridoxalphosphate-dependent enzymes, such as the covalent binding of the pyridoxalphosphate group to a lysine residue; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; Family membership.
 
 0.936
CAZ98616.1
Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor.A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family.Located in the cytoplasm; Family membership.
  
  
 
0.923
adhI
Alcohol dehydrogenase class 3 / S-(hydroxymethyl)glutathione dehydrogenase; Oxidizes long-chain aliphatic alcohols, long-chain hydroxylated fatty acids and S-hydroxymethylglutathione (hmGSH) in increasing order of preference. Shows little or no activity with short-chain aliphatic alcohols; Contains two zinc atoms. One is essential for catalytic activity while the other is not; Possibly involved in the metabolism of xenobiotics by cytochrome P450; Belongs to the zinc-containing alcohol dehydrogenase family, class- III subfamily; Localized in the cytoplasm; High confidence in function an [...]
 
 0.920
nitA
Nitrilases, involved in the reduction of organic nitrogen compounds and ammonia production, are enzymes that convert nitriles into their corresponding acids and ammonia by cleavage of the carbon-nitrogen bonds. They acts on a wide range of aromatic nitriles including (indol- 3-yl)-acetonitrile, and also on some aliphatic nitriles, and on the corresponding acid amides; Belongs to the CN hydrolase family; Localized in the cytoplasm; Specificity unclear.
   
 0.911
CAZ96907.1
Aldehyde dehydrogenases are enzymes which oxidize a wide variety of aliphatic and aromatic aldehydes using NADP as a cofactor. A glutamic acid and a cysteine residue have been implicated in the catalytic activity of mammalian aldehyde dehydrogenase. These residues are conserved in all the enzymes of this family; Located in the cytoplasm; Family membership.
  
  
 
0.910
CAZ95265.1
FAD-dependent amine oxidoreductase of unknown substrate specificity; Belongs to the amine oxydase family; Localized in the cytoplasm; Specificity unclear.
   
 0.908
panD
Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
     
 0.903
glxK
Glycerate kinase; Enzyme involved in glycine, serine and threonine metabolism, Glycerolipid metabolism and Glyoxylate and dicarboxylate metabolism; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the glycerate kinase type-1 family.
   
 
 0.903
panC
Pantoate-beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
     
 0.901
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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