STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fgeAC-alpha-formylglycine-generating protein; Converts newly synthesized inactive sulfatases to their active form by modifying an active site cysteine or serine residue to 3-oxoalanine; Putatively localized in the outer membrane; Specificity unclear. (381 aa)    
Predicted Functional Partners:
galK
Galactokinase; Involved in the first step of galactose metabolism that catalyzes the D-galactose to alpha-D-galactose-1-phosphate; Localized in the cytoplasm; High confidence in function and specificity; Belongs to the GHMP kinase family. GalK subfamily.
       0.773
CAZ96829.1
Sulfatase, family S1-14; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 14; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership.
 
   0.660
CAZ97734.1
Sulfatase, family S1-14; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 14; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership.
 
   0.648
CAZ97290.1
Sulfatase, family S1-17; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains a N-terminal transmembrane helix; Localized in the cytoplasmic membrane; Family membership.
 
   0.633
CAZ97675.1
Sulfatases, family S1-23; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 23; Signal peptide of lipoprotein cleaved between the residues 22 and 23, Localized in the outer membrane; Family membership.
 
   0.614
CAZ97781.1
Sulfatase, family S1-19; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Signal peptide cleaved between the residues 21 and 22; Localized in the periplasmic space; Family membership.
 
   0.602
CAZ94409.1
Sulfatase, family S1-16; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 16; Putative lipoprotein with a signal peptide cleaved between the residues 18 and 19. Possibly localized in the outer membrane; Family membership.
 
   0.577
CAZ97284.1
Sulfatase, family S1-19; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 19; Contains a N-terminal transmembrane segment; Localized in the cytoplasmic membrane; Family membership.
 
   0.572
CAZ97604.1
Sulfatase, family S1-22; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 22; Signal peptide of lipoprotein cleaved between the residues 17 and 18; Possibly localized in the outer membrane and/or in the cytoplasmic membranes; Family membership.
 
   0.568
CAZ97656.1
Sulfatase, family S1-17; The family 1 of sulfatases is composed of enzymes that require the posttranslational oxidation of a conserved cysteine (or serine) to a catalytic formylglycine to hydrolyze various sulfate ester substrates; Belongs to the family 1 of sulfatases (S1: formylglycine-dependent sulfatases), subfamily 17; Contains an uncleavable signal peptide; Localized in the cytoplasmic membrane; Family membership.
 
   0.557
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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