STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
CAZ95620.1Protein containing a N-terminal Type I phosphodiesterase domain and a C-terminal PA14 domain. These enzymes catalyze the cleavage of phosphodiester and phosphosulphate bonds in various compounds such as NAD, deoxynucleotides and nucleotide sugars. The PA14 domain sequence suggests a binding function, rather than a catalytic role and its distribution is compatible with carbohydrate binding; Signal peptide cleaved between the residues 23 and 24; Localized in the periplasm; Family membership. (548 aa)    
Predicted Functional Partners:
CAZ95623.1
Metallophosphoesterase; Protein containing a N-terminal Fibronectin type III domain, a central metallophosphoesterase domain and a second Fibronectin type III domain at the C-terminus. The most conserved regions in the metallophosphoesterase family centre around the metal chelating residues; Signal peptide cleaved between the residues 20 and 21; Localized in the periplasmic space; Family membership.
 
 
   0.933
CAZ95621.1
Metallohydrolase; Protein belonging to the Metallo-beta-lactamase superfamily. This superfamily includes various zinc-dependent hydrolases. The residues involved in metal ion binding are strictly conserved in this protein; Localized in the cytoplasm; Family membership.
 
     0.918
CAZ95622.1
Aminotransferases share certain mechanistic features with other pyridoxalphosphate-dependent enzymes, such as the covalent binding of the pyridoxalphosphate group to a lysine residue; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family; Localized in the cytoplasm; Family membership.
 
     0.893
CAZ95624.1
Conserved hypothetical periplasmic protein; Contains a signal peptide cleaved between the residues 18 and 19; Localized in the periplasm; Conserved hypothetical protein.
  
   
0.745
CAZ95619.1
SusD/RagB family lipoprotein; Protein probably involved in nutrient binding and belonging to the SusD/RagB family; Gene very often associated with a gene encoding for a TonB-dependent receptor or transducer; Contains a lipoprotein signal peptide cleaved between the residues 19 and 20; Probably localized in the outer membrane; Family membership.
 
     0.680
CAZ95617.1
Transcriptional regulator featuring a N-terminal helix-turn-helix DNA binding motif belonging to the Xre family and a C-terminal domain adopting a Cupin barrel fold. Localized in the cytoplasm; Specificity unclear.
 
     0.642
CAZ95618.1
TonB-dependent Receptor; Protein localized in the outer membrane involved in uptake of macromolecules that are too large to diffuse via the outer membrane porins channels or are encountered at very low concentrations. Contains a carboxypeptidase regulatory domain (22-96) and the Plug module (112-241) acting as a channel gate; The signal peptide is cleaved between the residues 17 and 18; Family membership.
 
     0.608
CAZ95615.1
Conserved oxidoreductase using FAD as cofactor. Contains two structural domains, a N-terminal beta/beta/alpha sandwich domain and a C-terminal alpha+beta fold domain. Localized in the cytoplasm; Specificity unclear.
 
     0.584
CAZ95614.1
Conserved hypothetical membrane protein; Contains twelve transmembrane helices; Localized in the cytoplasmic membrane; Conserved hypothetical protein.
 
     0.582
CAZ95616.1
Conserved hydrolase belonging to the haloacid dehalogenase family, which includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure consists of two domains, a four helix bundle domain and a alpha/beta domain. Localized in the cytoplasm; Family membership.
 
     0.494
Your Current Organism:
Zobellia galactanivorans
NCBI taxonomy Id: 63186
Other names: CCUG 47099, CIP 106680, Cytophaga drobachiensis, DSM 12802, Flavobacterium droebachense, Pseudomonas droebachense, Z. galactanivorans, Zobellia galactanivorans corrig. Barbeyron et al. 2001, Zobellia galactanovorans, strain Dsij
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